Essays about: "3D cell culture"

Showing result 6 - 10 of 12 essays containing the words 3D cell culture.

  1. 6. Identification of changes in biomarkers relevant for breast cancer biology occurring in a novel 3D-Biosilk model

    University essay from KTH/Proteinvetenskap

    Author : Emmy Ståhl; [2021]
    Keywords : 3D-Biosilk; breast cancer; 3D cell culture; recombinant spider silk; ZO-1; 3D-Biosilk; bröstcancer; 3D cellkultur; rekombinant spindeltråd; ZO-1;

    Abstract : Bröstcancer är den vanligaste formen av cancer som drabbar kvinnor. Det är en heterogen och komplex sjukdom som består av flera undergrupper, var och en med distinkt morfologi och kliniska implikationer [1]. För att modellera och studera cellbiologi, vävnadsmorfologi, molekylära mekanismer och läkemedels effekter används cellkulturer [2]. READ MORE

  3. 7. Explorative bioinformatic analysis of cardiomyocytes in 2D &3D in vitro culture system

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Sruthy Janardanan; [2021]
    Keywords : Cardiomyocytes; Pluripotent stem cells; 2D; 3D; differentially expressed genes; Hub nodes; Hub-Bottleneck nodes;

    Abstract : The in vitro cell culture models of human pluripotent stem cells (hPSC)-derived cardiomyocytes (CMs) have gained a predominant value in the field of drug discovery and is considered an attractive tool for cardiovascular disease modellings. However, despite several reports of different protocols for the hPSC-differentiation into CMs, the development of an efficient, controlled and reproducible 3D differentiation remains challenging. READ MORE

  4. 8. Knockout studies of Panc1 cells

    University essay from KTH/Tillämpad fysik

    Author : Martin Sundin; [2021]
    Keywords : PDAC; crosstalk; stroma; spheroid; western blot; viability; gemcitabine.; PDAC;  verh rning; stroma; sf roid; western blot; viabilitet; gemcitabine.;

    Abstract : Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal form of cancerwith very few available treatment options of which none has great effect.Cancer cells and stromal cells such as stellate cells which exist in abundancein PDAC interact by crosstalk, resulting in a tumorigenic collective response. READ MORE

  5. 9. How Topography Influences the Fate of Human Neural Progenitor Cells

    University essay from Lunds universitet/Tillämpad biokemi; Lunds universitet/Beräkningskemi

    Author : Jacob Karlström; [2020]
    Keywords : biomaterials; cell culture; electrospinning; nanofibers; 3d; neural progenitor cells; in vitro models; nanotopography; blebbistatin; mechanotransduction; nucleus analysis; immunocytochemistry; differentiation; applied biochemistry; tillämpad biokemi; Biology and Life Sciences; Technology and Engineering;

    Abstract : Novel biomimetic three-dimensional scaffolds have emerged over the last decades, and are promising for applications in regenerative therapies, as well as in in vitro disease modelling and drug testing. Thanks to their added dimension, these scaffolds are able to more accurately mimic the topography of native cellular microenvironments compared to traditionally used two-dimensional culture substrates. READ MORE

  6. 10. Patient-derived organoid culture for 3D culture of colorectal cancer, renal cancer and osteosarcoma

    University essay from Uppsala universitet/Institutionen för kvinnors och barns hälsa

    Author : Seiko Johansson; [2019]
    Keywords : FMCA; Anticancer drugs; Survival index; BME-gel; VEGF;

    Abstract : It is always important to choose appropriate anticancer drugs for cancer patients. At RCL, a division of Uppsala university hospital, drug resistance profiles of patients are evaluated by a cell viability assay called FMCA. READ MORE