Essays about: "Alternative Splicing"

Showing result 1 - 5 of 16 essays containing the words Alternative Splicing.

  1. 1. The effect of TRAP150 on HPV16 E1 gene regulation

    University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Author : Emma Svanberg Frisinger; [2023]
    Keywords : ;

    Abstract : Human papilloma virus (HPV) is a small DNA virus that is known as the causative agent in cervical cancer. The virus is found worldwide and causes more than 300 000 deaths yearly. Although there are many types of HPV, HPV16 is found in 99 % of cervical cancer cases. READ MORE

  3. 2. Differential expression and function of fubl-1 gene isoforms in C. elegans

    University essay from Uppsala universitet/Molekylärbiologi; Uppsala universitet/Mikrobiologi och immunologi; Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Joel Pålsson; [2022]
    Keywords : isoform; gene expression; C elegans; protein; alternative splicing; isoformer; genuttryck; C elegans; protein; alternativ splicing;

    Abstract : Alternative splicing is the process of producing a variety of transcripts from one and the same gene. This adds further possible variability to gene expression and can in theory mean that one protein coding gene can produce multiple proteins with potentially different functions. READ MORE

  4. 3. Systems biology of deregulated splicing in cancer. A pan-cancer analysis of dysfunctional splicing machinery and alternative splicing events.

    University essay from

    Author : Leticia Castillon; [2021-08-06T14:57:24Z 2021-08-06T14:57:24Z 2021 2020]
    Keywords : multi-omics; splicing; alternative splicing; deep learning; cancer; transcriptome;

    Abstract : The deregulation or disruption of the splicing process has been shown to play a role in the onset, development, and even response to treatment of some malignancies. Partly due to our incomplete understanding of the mechanism and regulation behind splicing and alternative splicing, the importance of aberrant splicing in oncogenesis is not yet understood. READ MORE

  5. 4. Isoform 2 of DLG2 gene as a possible candidate tumour suppressor of neuroblastoma

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Paula Camargo Romera; [2021]
    Keywords : ;

    Abstract : Neuroblastoma (NB) is the most frequent extracranial solid tumour in childhood. The clinical diagnosis of NB is difficult due to the age of the patient and the vague appearance of the symptoms. Moreover, there are two groups of aggressive NBs, one with MYCN amplification and the other with an 11q deletion. READ MORE

  6. 5. Impact of SETD2 mutation in the regulation of Autophagy in Clear Cell Renal Cell Carcinoma Cells

    University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Author : Hanzhao Zhang; [2018]
    Keywords : ;

    Abstract : Background: Autophagy is an important cellular pathway in cell growth and maintenance, during which unnecessary organelles and materials in cells can be degraded. Regulation of autophagy is related to tumorigenesis. READ MORE