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1. 1. Improving the Modeling Framework for DCE-MRI Data in Hepatic Function Evaluation

   University essay from Institutionen för medicin och hälsa; Hälsouniversitetet

   Author : Anneli Mossberg; [2013]
   Keywords : DCE-MRI; modeling; irregular sampling; spatio-temporal standard deviation estimation; sampling time optimization; regional optimization; liver function evaluation; systems biology;

   Abstract : Background Mathematical modeling combined with prior knowledge of the pharmacokinetics of the liver specific contrast agent Gd-EOB-DTPA has the potential to extract more information from Dynamic Contrast Enhanced Magnetic Resonance Imaging (DCE-MRI) data than previously possible. The ultimate goal of that work is to create a liver model that can describe DCE-MRI data well enough to be used as a diagnostic tool in liver function evaluation. READ MORE