Essays about: "Anticancer drug development"

Found 3 essays containing the words Anticancer drug development.

  1. 1. Expanding the application of a novel proteomics tool for drug target and mechanism identification

    University essay from Uppsala universitet/Analytisk kemi

    Author : Linnéa Yuan Andersson; [2022]
    Keywords : ;

    Abstract : In drug discovery and development, characterization of the drug targets and mechanisms of action is an essential step. ProTargetMiner is a publicly available proteome signature library of anticancer molecules and its automated bioinformatics platform can be used for drug target and mechanism deconvolution. READ MORE

  2. 2. ProTargetMiner one step further : Deep comparative proteomics of Dying vs. Surviving cancer cells treated with anticancer compounds

    University essay from Uppsala universitet/Analytisk kemi

    Author : Albin Lundin; [2022]
    Keywords : Cancer; Surviving VS Dying; Proteomics; Comparative Proteomics; RKO; A549; MCF7; drug discovery; life; death; life and death decisions; target ranking; OPLS-DA; drug targets; novel anticancer agents;

    Abstract : Cancer is a leading cause of mortality worldwide, responsible for nearly one in six deaths. Thus, there is a need for a greater understanding of cancer for the development of novel therapeutics. This master thesis project aims to compare the proteome signatures between dying and surviving cancer cells treated with diverse anticancer drugs. READ MORE

  3. 3. Do the new signal transduction modulators have activity in vitro in tumor cells from ovarian carcinoma and lymphoma?

    University essay from Institutionen för medicinsk biokemi och mikrobiologi

    Author : Desiré Lundin; [2005]
    Keywords : Anticancer drug development; ovarian carcinoma; lymphoma; FMCA; cytotoxic drugs; in vitro assay;

    Abstract : During the last decades, chemotherapy with cytotoxic drugs has played a significant role in cancer therapy. It’s important to develop new anticancer drugs, and drug sensitivity testing in vitro can be used to find the right diagnosis for the newly developed substances. READ MORE