Essays about: "Lovisa Hemmingsson"

Found 2 essays containing the words Lovisa Hemmingsson.

  1. 1. Bri2 BRICHOS domain : Eukaryotic expression and importance of strictly conserved cysteine residues

    University essay from Linköpings universitet/Institutionen för fysik, kemi och biologi

    Author : Lovisa Hemmingsson; [2017]
    Keywords : Bri2 BRICHOS; Aß; Chaperone; Amyloid fibril formation; Alzheimer disease; Eukaryotic expression; Cysteine residues;

    Abstract : Alzheimer’s disease (AD), the most common form of dementia is associated with fibril formation of amyloid-ß peptides (Aß). Aß, proteolytically derived from Aß precursor protein (AßPP), is the major component of amyloid plaques in AD brains. READ MORE

  3. 2. In vitro studies of Thiopurine S-Methyltransferase: Ligand binding interactions and development of a new enzymatic activity assay for TPMTwt, TPMT*6 and TPMT*8

    University essay from Linköpings universitet/Institutionen för fysik, kemi och biologi; Linköpings universitet/Tekniska fakulteten

    Author : Lovisa Hemmingsson; Johan Klasén; [2015]
    Keywords : Thiopurine S-Methyltransferase; 6-mercaptourine; methotrexate; isothermal titration calorimetry; fluorescence spectroscopy;

    Abstract : Acute lymphoblastic leukemia, one of the most malignant cancer forms in children is commonly treated with the thiopurine 6-mercaptopurine (6-MP) in combination with a high dose of methotrexate (MTX). 6-Mercaptopurine is in the body metabolized by the enzyme thiopurine S-methyltransferase (TPMT). READ MORE