Essays about: "Pyrrolidines"

Found 1 essay containing the word Pyrrolidines.

1. 1. Synthesis of Substituted Pyrrolidines

   University essay from KTH/Skolan för kemivetenskap (CHE)

   Author : Olof Sjölin; [2016]
   Keywords : Pyrrolidines; Multistep synthesis; Fragment-based drug design; Drug discovery; Organic chemistry;

   Abstract : The task of medicinal chemists in a drug discoveryproject is to synthesize/design analogues to the screening hits, simultaneouslyincreasing target potency and optimizing the pharmacological properties.  This requires a wide selection of moleculesto be synthesized, where both synthetic feasibility and price of startingmaterials are of great importance. READ MORE