Essays about: "Substantia nigra"

Found 5 essays containing the words Substantia nigra.

  1. 1. Non-motor symptoms and their use as markers for prodromal and early Parkinson's disease

    University essay from Uppsala universitet/Institutionen för organismbiologi; Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Aubree Stephens; [2021]
    Keywords : Neurology; Parkinson s; non-motor symptom; prodromal;

    Abstract : Parkinson’s Disease (PD) is the second most common neurodegenerative disorder. It is a disease with a broad spectrum of symptoms, both motor and non-motor, but is often only diagnosed when the motor symptoms begin to appear. READ MORE

  2. 2. The subthalamic nucleus in health and disease

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Yu Zhang; [2020]
    Keywords : ;

    Abstract : Parkinson’s disease (PD) is the second most common neurodegenerative disorder in the world. PD is caused by degeneration of the dopaminergic neurons in the substantia nigra pars compacta (SNc). READ MORE

  3. 3. Optimization of PCR protocols used for genotyping transgenic mice & Evaluation of a method for co-detecting mRNA and protein

    University essay from Uppsala universitet/Jämförande fysiologi

    Author : Amanda Isaksson; [2017]
    Keywords : Ventral tegmental area; Substantia nigra; Parkinson’s disease; transgenic mice; Cre-Lox recombination;

    Abstract : The aim of the current study was divided into two separate goals, (i) optimization of a number of PCR-based protocols employed for genotyping transgenic mouse lines and (ii) evaluating a protocol for co-detection of mRNA and its correlated protein in the mouse midbrain. The optimization was performed on PCR protocols for genotyping the following transgenic mouse lines; Dat-Cre, Vglut2-Lox, Vglut2-Cre and Vmat2-Lox. READ MORE

  4. 4. Identification and characterization of genes that are involved in reward mechanisms in ethanol self-administration

    University essay from SLU/Dept. Of Plant Biology

    Author : Hung Trinh; [2009]
    Keywords : brain reward pathway; ethanol self-administration; neurotransmitter receptor; real-time PCR; mRNA; VTA; NAc; Sn; CPu;

    Abstract : Alcohol addiction is one of the most common drug addictions amongst societies. Alcohol abuse, can lead serious injuries, severe diseases or even death. Despite intensive research, complete knowledge about alcohol addiction and a specific "ethanol receptor" has not been found yet. READ MORE

  5. 5. Effects of glial cell line-derived neurotrophic factor (GDNF) on mouse fetal ventral mesencephalic tissue

    University essay from Institutionen för biologi och kemiteknik

    Author : Nina Nevalainen; [2008]
    Keywords : Parkinson s disease; dopamine; glial cell line-derived neurotrophic factor GDNF ; ventral mesencephalon; astrocytes;

    Abstract : The symptoms of Parkinson's disease occur due to degeneration of dopamine neurons in substantia nigra. It has been demonstrated that glial cell line-derived neurotrophic factor (GDNF) is a potent neurotrophic factor when it comes to protect and enhance survival of dopamine neurons in animal models of Parkinson's disease. READ MORE