Essays about: "autofagi"

Found 3 essays containing the word autofagi.

  1. 1. Autophagy and senescence in primary human bronchial epithelial cells in the context of COPD

    University essay from Lunds universitet/Examensarbeten i molekylärbiologi

    Author : Annie Vegraeus; [2023]
    Keywords : Biology and Life Sciences;

    Abstract : Chronic obstructive pulmonary disease (COPD) is the third largest cause of death worldwide, with its most prominent risk factor being inhalation of smoke and pollutants. In this project, we studied two processes that are involved in COPD: autophagy and cellular senescence. READ MORE

  2. 2. Crystallization, optimization, and crystal structure determination of ligands in complex with galectin-8N

    University essay from Lunds universitet/Kemiska institutionen

    Author : George Larsson; [2022]
    Keywords : Biochemistry; Structural Biochemistry; Galectin-8; Protein Crystallization; Chemistry;

    Abstract : This thesis focuses on the protein “galectin-8N” which is a lectin protein that takes part in several physiological functions such as inflammation, autophagy, cell migration, and more. The project has three objectives: to observe and increase the reproducibility of crystallization of two variants (wildtype and mutant) of the human protein galectin-8N and to analyze the binding site when three different novel ligands are each inserted. READ MORE

  3. 3. Why does trehalose not improve autophagy in the SOD1G93A transgenic mouse model of familial ALS?

    University essay from SLU/Dept. of Biomedical Sciences and Veterinary Public Health

    Author : Karolina Karlsson; [2015]
    Keywords : trehalose; SOD1; amyotrophic lateral sclerosis; ALS; autophagy; plaque; neurodegeneration; trehalos; SOD1; amyotrofisk lateralskleros; ALS; autofagi; plack; neurodegeneration;

    Abstract : Amyotrophic lateral sclerosis is one of the major neurodegenerative diseases, causing an ascending paralysis that usually kills the patient within a few years from disease onset. The motor neurons show aggregates of proteins which in approximately 20 % of cases of the familial form contain mutated SOD1 protein. READ MORE