Essays about: "autoimmune diseases"

Showing result 1 - 5 of 49 essays containing the words autoimmune diseases.

  1. 1. Profiling the Blood Proteome in Autoimmune Disease Using Proximity Extension Assay

    University essay from KTH/Proteinvetenskap

    Author : Julia Asp; [2023]
    Keywords : Plasma proteomics; proximity extension assay; autoimmune disease; differential expression; machine learning; biomarkers; Plasma proteomik; proximity extension assay; autoimmuna sjukdomar; differentiellt proteinuttryck; maskininlärning; biomarkörer;

    Abstract : Autoimmuna sjukdomar är en samling komplexa, kroniska, inflammatoriska sjukdomstillstånd som kännetecknas av dysreglering av immunsystemet, vilket resulterar i inflammation och skada av vävnader, celler och organ. Dessa sjukdomar har en betydande inverkan på individens livskvalitet och bidrar ofta till ökad dödsrisk där komorbiditeter föreligger. READ MORE

  3. 2. Prediction of Persistence to Treatment for Patients with Rheumatoid Arthritis using Deep Learning

    University essay from KTH/Skolan för elektroteknik och datavetenskap (EECS)

    Author : Serkan Arda Yilal; [2023]
    Keywords : Variational Autoencoders; Rheumatoid Arthritis; Precision Medicine; Treatment Prediction; Deep Learning; Supervised Learning; Rheumatoid Artrit; Precisionsmedicin; Behandlingsförutsägelse; Djupinlärning; Övervakat lärande;

    Abstract : Rheumatoid Arthritis is an inflammatory joint disease that is one of the most common autoimmune diseases in the world. The treatment usually starts with a first-line treatment called Methotrexate, but it is often insufficient. One of the most common second-line treatments is Tumor Necrosis Factor inhibitors (TNFi). READ MORE

  4. 3. Elevated IgG4 is associated with higher risk for cholangitis, cirrhosis, ERCP and liver-transplantation among patients with primary sclerosing cholangitis

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Jennifer Carlsson; [2022]
    Keywords : Primary sclerosing cholangitis; liver disease; IgG;

    Abstract : Primary sclerosing cholangitis (PSC) is a rare inflammatory chronic liver disease that causes damage to the intra- and or extrahepatic bile ducts leading to cholestasis. As the disease proceeds the development of cirrhosis and eventually liver failure occurs. READ MORE

  5. 4. Imaging of the Cytosolic Antibody Receptor TRIM21

    University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Author : Þórunn Stefánsdóttir; [2022]
    Keywords : TRIM21; ProteinStructure; Antibody; cryo-EM; Gel-Filtration SizeExclusion Chromatography ; Immunology; ProteinPurification; SDS-PAGE; TRIM21; Proteinstruktur; Antikroppar; cryo-EM; Gel-filtreringsKromatografi; Immunologi; ProteinRening; SDS-PAGE;

    Abstract : TRIM21 is a cytosolic ubiquitin ligase and an antibody receptor that providesa last line of defense against invading pathogens. By utilizing the diversity ofantibody repertoire to identify pathogens, TRIM21 serves as a link betweenintrinsic cellular defense and adaptive immunity. READ MORE

  6. 5. Profiling the autoantibody repertoire in systemic sclerosis

    University essay from KTH/Proteinvetenskap

    Author : Emmie Pohjanen; [2021]
    Keywords : Systemic sclerosis; rheumatology; autoimmunity; autoantibody; biomarkers; Systemisk skleros; reumatologi; autoimmunitet; autoantikropp; biomarkörer;

    Abstract : Systemisk skleros (SSc) är en autoimmun rheumatisk sjukdom som kännetecknas av fibros i huden och/eller de interna organen, vaskulopati och en autoimmun reaktion från immunförsvaret, med eller utan specifika autoantikroppsprofiler. Diagnostisering och sjukdomsbehandling försvåras av sjukdomens heterogena natur. READ MORE