Essays about: "cGMP"

Found 4 essays containing the word cGMP.

1. 1. Development and validation of an ultrahigh-performance liquid chromatography method for identity, assay and impurity testing of nicotine and preservatives in nicotine nasal spray

   University essay from Lunds universitet/Centrum för analys och syntes

   Author : Amane Kandas; [2021]
   Keywords : Nicotine; Nicotine nasal spray; Ultrahigh-performance liquid chromatography; Development; Validation; Technical analytical chemistry; Chemistry;

   Abstract : The topic of this study is to develop and validate an analysis method of nicotine nasal spray produced at McNeil AB. When developing the analysis method, several parameters were determined in advance to make the method more similar to other analysis methods at the company, making it more practical. READ MORE

3. 2. Pre-formulation of a novel nucleotide analogue

   University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

   Author : Mariam Rabizadegan; [2019]
   Keywords : Pre-formulation; pharmaceutical development;

   Abstract : Previous studies have shown that the molecule MR1, a cGMP analogue, may be a suitable drug for neurodegenerative eye diseases. These diseases cause the eyesight to greatly deteriorate which in turn can result in the patient becoming blind. READ MORE

4. 3. Value Stream Mapping as a Basis for Process Improvement in the Pharmaceutical Industry

   University essay from Lunds universitet/Teknisk logistik

   Author : Jesper Manning; Filip Sörlin; [2017]
   Keywords : Lean manufacturing; Value stream mapping; Lean production; Pharmaceutical industry; cGMP; Good Manufacturing Practice; Technology and Engineering;

   Abstract : Background - The company is a Swedish manufacturer, developer and contract manufacturer of pharmaceuticals. In the last couple of years, the company has entered a growth phase which has led to issues with the internal processes such as material flow, warehouse operations and processes related to the production. READ MORE

5. 4. Human platelet aggregation induced via protease-activated receptor 1 (PAR1)signaling is reversed by nitric oxide (NO) through inhibition of a Rho-kinase/ROCK-mediated pathway

   University essay from Institutionen för fysik, kemi och biologi

   Author : Patrik Björn; [2010]
   Keywords : Platelet; nitric oxide; PAR1; Rho-kinase; ROCK;

   Abstract : Human platelets are constantly regulated by activating and inhibitory effectors. Thrombin,the most potent platelet agonist, induces signaling through the protease-activated receptors(PARs) 1 and 4 which in turn convey their signal by coupling to G-proteins. READ MORE