Essays about: "copy number variants"

Found 4 essays containing the words copy number variants.

  1. 1. Detecting structural variants in the DNA of the inbred Scandinavian wolf

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Lars Huson; [2023]
    Keywords : animal; animal population; bioinformatics; biological sciences; biology; Canis lupus; CNV; conservation genetics; conservation genomics; copy-number variation; DNA; endangered population; endangered species; evolution; evolutionary biology; extinction; genetic diversity; genetics; genetic variation; genomes; genomics; grey wolf; inbreeding; inbreeding depression; indel; mutation; pedigree; population genetics; population genomics; Scandinavia; smoove; snakemake; structural variant; SV; wolf; wolves;

    Abstract : Only 40 years ago, just three individuals made the journey from Finland/Russia to found the current wolf population in the southwest of Sweden. This population, that to this date descends from less than 10 founders, has a substantial increased extinction risk due to inbreeding. READ MORE

  3. 2. Detection and characterization of genomic regions associated to Dilated Cardiomyopathy in Great Danes

    University essay from SLU/Dept. of Animal Breeding and Genetics

    Author : Ana Letícia Kolicheski; [2012]
    Keywords : Great Dane; DCM; cardiomyopathy; dog; GWAS;

    Abstract : Canine dilated cardiomyopathy (DCM) is a lethal myocardial disease prevalent in large and giant-sized dog breeds, including the Great Dane (GD). The goal of this study was to identify genetic risk factors for DCM and to contribute to a future development of DCM genetic markers in order to facilitate disease diagnosis and risk allele detection. READ MORE

  4. 3. Copy number variations as potential biomarkers for disease development in Breast Cancer

    University essay from SLU/Dept. of Microbiology

    Author : Reddy Prakash Kancherla; [2011]
    Keywords : Breast cancer; Copy number variation; IFNAR1; VNTR;

    Abstract : Breast cancer is second foremost cause of deaths in women caused by malignant tumor.Comparing genetic profiles of cells surrounding the tumor and blood from same patient may reveal de‐novo somatic aberrations that may predispose normal cells to cancer cells. READ MORE

  5. 4. Difference in copy number variants in peripheral blood and bone marrow detected by SNP-array

    University essay from Biomedicinsk laboratorievetenskap

    Author : Anna Mattsson; [2011]
    Keywords : SNP-array; chromosomes; copy number variants; leukemia; aberrations; 11q23;

    Abstract : .... READ MORE