Essays about: "core genome"
Showing result 1 - 5 of 11 essays containing the words core genome.
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1. Pseudomonas aeruginosa gene expression analysis using pangenome and PAO1 reference genomes
University essay from Lunds universitet/Examensarbeten i bioinformatikAbstract : Development in sequencing technologies has made the analyses of genetic material much more accessible. Processing sequenced data for an accurate analysis comes with its challenges, especially with the studies in microbial in clinical in vivo samples where difficulties in the collection of these samples for sequencing could lower the quality and contamination from the human host which might affect the accuracy of downstream analysis. READ MORE
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2. Evaluation and implementation of quality control parameters for genome-wide DNA methylome sequencing
University essay from Högskolan i Skövde/Institutionen för biovetenskapAbstract : Epigenomics is the study of modifications to the genetic material without changes to the DNA sequence, one such modification is methylation of nucleotides. DNA methylation is associated with gene regulation and is studied in a variety of fields such as cancer and ageing. READ MORE
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3. Cancer Driver Gene Detection using Deep Convolutional Neural Networks on H3K4me3 Enrichment Profiles
University essay from Lunds universitet/Institutionen för astronomi och teoretisk fysik - Genomgår omorganisationAbstract : In spite of our current knowledge regarding the biology underlying cancer genesis, reliable methods for the discovery of cancer driver (CD) genes are still in great need. The rather recent incorporation of epigenetic markers to the cancer paradigm has nevertheless opened the door for the development of new computational approaches to the problem. READ MORE
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4. Study of the Genetic Dynamics in Pan-genomes for Six Bacterial Species
University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologiAbstract : Foodborne diseases are a growing health problem today and can be caused by eating food contaminated with bacteria. To monitor known foodborne diseases, institutions keep track of bacteria in surveillance projects. Whole genome sequencing is becoming the new standard method for comparing isolates, which generates large amounts of data. READ MORE
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5. Developing a web based tool for identification of disease modules
University essay from Högskolan i Skövde/Institutionen för biovetenskapAbstract : Complex diseases such as cancer or obesity are thought to be caused by abnormalities in multiple genes and cannot be derived to one specific location in the genome. It has been shown that identification of disease associated genes can be made through looking at interaction patterns in a protein‐protein interaction network, where the disease associated genes are represented in clusters, or disease modules. READ MORE
