Essays about: "cycle sequencing"

Showing result 1 - 5 of 18 essays containing the words cycle sequencing.

  1. 1. Investigating ERβ chromatin binding and its potential interaction with LRH-1 in an ovarian context

    University essay from KTH/Proteinvetenskap

    Author : Mick Phenphak; [2023]
    Keywords : estrogen receptor beta; ovary; granulosa cells; ChIP; qPCR; östrogen receptor beta; äggstock; granulosa celler; ChIP; qPCR;

    Abstract : Invasiv äggstockscancer anses vara en av de mest dödligaste gynekologiska maligniteterna. Granulosacelltumör i äggstocken är en sällsynt subtyp av äggstockstumör, som utgör 1–5% av alla äggstockstumörer. De kan kännetecknas av den långsamma tillväxthastigheten och produktionen av höga östrogennivåer. READ MORE

  3. 2. Predicting tumour growth-driving interactions from transcriptomic data using machine learning

    University essay from Uppsala universitet/Neuroonkologi och neurodegeneration

    Author : Mathilda Stigenberg; [2023]
    Keywords : cancer; immunology; cell-cell interactions; deep learning; variational autoencoder; supervised variational autoencoder; tumour microenvironment; single-cell RNA sequencing; spatial transcriptomics; breast cancer; machine learning;

    Abstract : The mortality rate is high for cancer patients and treatments are only efficient in a fraction of patients. To be able to cure more patients, new treatments need to be invented. Immunotherapy activates the immune system to fight against cancer and one treatment targets immune checkpoints. READ MORE

  4. 3. Single-cell RNA-seq mapping of chicken leukocytes : An investigation into single-cell transcriptomics as an alternative to traditional immunological methods within non-traditional model organisms

    University essay from Uppsala universitet/Mikrobiologi och immunologi

    Author : Matilda Maxwell; [2023]
    Keywords : Bioinformatics; scRNA-seq; avian; immunology; Seurat; leukocytes; chicken; gallus gallus; 10x genomics; PCA;

    Abstract : The immune system is a complex infrastructure where many cells interact with each other and perform duties depending on their type and function. When using traditional immunological methods in studying non-traditional model organisms, such as birds, challenges arise. READ MORE

  5. 4. The influence of diel cycles on the bacterial community composition of two boreal lakes : A case study in Jämtland

    University essay from Uppsala universitet/Limnologi; Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Sofia Papadopoulou; [2021]
    Keywords : freshwater; lake; diel cycle; bacterioplankton; bacterial community composition;

    Abstract : In the Boreal region, the length of day and night varies extremely over the year and organisms are exposed to different diel (24 h) fluctuations of light and temperature. Among them are pelagic populations of bacteria that are ubiquitous in freshwater ecosystems. READ MORE

  6. 5. Dual RNA-seq analysis of host-pathogen interaction in Eimeria infection of chickens

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Arnar Kári Sigurðarson Sandholt; [2020]
    Keywords : Dual RNA-seq; Bioinformatics; Eimeria tenella; Gene co-expression networks; Chicken;

    Abstract : Eimeria tenella is a eukaryotic, intracellular parasite that, along with six other Eimeria species, causes coccidiosis in chickens. This disease can result in weight loss or even death and is estimated to cause 2 billion euros of damages to the chicken industry each year. While much is known of the life cycle of E. READ MORE