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Found 5 essays matching the above criteria.

  1. 1. Quantification of cerebral blood flow with 15O-water PET : A comparison study between PET/CT and PET/MR and two different blood sampling instruments

    University essay from Umeå universitet/Institutionen för fysik; Umeå universitet/Diagnostisk radiologi

    Author : Amanda Eriksson; [2021]
    Keywords : Cerebral Blood Flow; CBF; oxygen-15-labelled water; PET CT; PET MR; Quantification of CBF; Image Derived Input Function; IDIF; Blood Sampled Input Function; BSIF; Arterial Input Function; AIF; Tracer Kinetic Modelling; Single Tissue Compartmental Model; 1TCM;

    Abstract : Cerebral blood flow quantification is a vital diagnostic tool for disease monitoring and used for diagnosing a variation of pathological conditions. The human brain requires roughly about 20 % of the total cardiac output to sustain normal functioning, hence the perfusion of blood is an important factor to deliver oxygenated blood. READ MORE

  2. 2. Modelling and simulation of antibody purification

    University essay from Lunds universitet/Kemiska institutionen; Lunds universitet/Kemiteknik (CI)

    Author : Ferran Perez Serrano; [2014]
    Keywords : Chromatography; Protein A; Cationic Ion Exchange Chromatography; Antibody Purification.; Technology and Engineering;

    Abstract : Due to their high specificity against target antigens, monoclonal antibodies (mAbs) have proven to be a very powerful tool for diagnostic and therapeutic purpose against several diseases. Currently there are over 26 mAb approved for therapeutic use by the FDA. The manufacture of mAbs is a complex process where purification plays a key role. READ MORE

  3. 3. Improving the Modeling Framework for DCE-MRI Data in Hepatic Function Evaluation

    University essay from Institutionen för medicin och hälsa; Hälsouniversitetet

    Author : Anneli Mossberg; [2013]
    Keywords : DCE-MRI; modeling; irregular sampling; spatio-temporal standard deviation estimation; sampling time optimization; regional optimization; liver function evaluation; systems biology;

    Abstract : Background Mathematical modeling combined with prior knowledge of the pharmacokinetics of the liver specific contrast agent Gd-EOB-DTPA has the potential to extract more information from Dynamic Contrast Enhanced Magnetic Resonance Imaging (DCE-MRI) data than previously possible. The ultimate goal of that work is to create a liver model that can describe DCE-MRI data well enough to be used as a diagnostic tool in liver function evaluation. READ MORE

  4. 4. Evaluation of a diagnostic tool for use during system development and operations

    University essay from Institutionen för systemteknik

    Author : Daniel Andersson; Patrik Sköld; [2007]
    Keywords : Model based diagnosis; artificial intelligence; diagnostic modelling tool; Rodon; failure analysis; generation of decision;

    Abstract : Rodon is a diagnostic tool developed by Sörman. SAAB’s interest in Rodon regards the possibility to use the tool for development and operations of aircraft systems. The main goal of this thesis was to evaluate the capacity of Rodon and determine how SAAB can use the diagnostic tool during development and operations. READ MORE

  5. 5. On simulation of surface discharges at variable voltage frequency

    University essay from KTH/Elektroteknisk teori och konstruktion

    Author : Nadejda Jäverberg; [2007]
    Keywords : partial surface discharge; modelling; capacitive-resistive network;

    Abstract : Isolationsdiagnostik är ett redskap som är av stor betydelse för underhållsoptimering av elektriska anläggningar. Ett av de möjliga mått på isolationsförsämring som kan användas i diagnosticeringssyfte är partiella urladdningar. READ MORE