Essays about: "functional enrichment analysis"

Showing result 1 - 5 of 8 essays containing the words functional enrichment analysis.

  1. 1. Unraveling gene gene interactions in rheumatoid arthritis

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Saad Salman Khan Lodhi; [2021]
    Keywords : ;

    Abstract : Rheumatoid arthritis (RA) is a systematic autoimmune disorder characterized by a persistent joint inflammation. A subset of HLA-DRB1 alleles known as shared epitope (SE) are the strongest genetic risk factors to develop anti-citrullinated protein antibody positive (ACPA-positive) RA. READ MORE

  3. 2. Investigation of the gene expression landscape of human skin wounds

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Yuen Ting Cheung; [2021]
    Keywords : bioinformatics; wound healing; lncRNA; long non-coding RNA;

    Abstract : Wound healing is a complex physiological process. Effective wound healing enables the skin barrier function to be restored once the skin is injured. However, due to the complex nature of wounds, the mechanisms underlying tissue repair are still poorly understood. READ MORE

  4. 3. Non-coding constraint mutations impact the gene regulatory system in osteosarcoma

    University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi; Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Raphaela Pensch; [2021]
    Keywords : cancer; osteosarcoma; cancer genomics; evolutionary constraint; non-coding mutations; gene regulation;

    Abstract : The non-coding space makes up around 98 % of the genome, but cancer-driving mutations have so far mostly been discovered in protein-coding regions. The majority of somatic non-coding mutations are neutral passenger mutations and identifying non-coding mutations with driving roles in cancer poses a challenge. READ MORE

  5. 4. Model Dialogues: 3D models as active resources – an experiment in data enrichment of 3D modelled lithic artefacts

    University essay from Lunds universitet/Arkeologi

    Author : Michael Harris; [2020]
    Keywords : Digitisation; Visualisation; Illustration; Slow Archaeology; Photogrammetry; Digital Archaeology; Agisoft Metashape; Meshlab; Blender; 3DHOP; Metadata; Formation Processes; Use-Wear Analysis; Chaîne opératoire; History and Archaeology;

    Abstract : This thesis seeks to explore the potential for 3D archaeological datasets to become the ‘living resources’ advocated by Morgan and Wright (2018). This process is examined through lenses of object agency, object biography, Chaîne opératoire, formation processes and posthumanist theory with an aim to assess the capacity of digital approaches for enabling the self-reflexive ‘slow archaeology’ idealised by Caraher (2016). READ MORE

  6. 5. Bridging inflammatory bowel diseases and hepatobiliary disorders through pathway enrichment and module-based approach

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Alaa Saloum; [2020]
    Keywords : ;

    Abstract : Inflammatory bowel diseases (IBD) including Crohn’s disease (CD) and ulcerative colitis (UC) are associated with various hepatobiliary disorders. Two of the chronic hepatobiliary disorders that may coexist with inflammatory bowel diseases are: primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC). READ MORE