Essays about: "mutant"

Showing result 1 - 5 of 122 essays containing the word mutant.

  1. 1. Gene expression editing in myeloma cell lines using CRISPR/Cas9 technique

    University essay from Uppsala universitet/Institutionen för medicinsk cellbiologi

    Author : Wilma Wadman; [2023]
    Keywords : BMPR1A; BMPR2; bone morphogenetic protein; gene knockout; multiple myeloma;

    Abstract : Multiple myeloma, or myeloma, is a bone marrow cancer which characterizes by uncontrolled proliferation of mutant plasma cells. It is a disease that claims many lives every year, mostly due to the absence of curative treatment. Finding a suitable treatment is therefor of great importance. READ MORE

  3. 2. Increased catalytic activity of engineered next generation mutant aldolase

    University essay from Uppsala universitet/Biokemi

    Author : Eda Sönmez; [2023]
    Keywords : ;

    Abstract : .... READ MORE

  4. 3. Design, production and in vitro evaluation of brain shuttle scFc-scFv8D3 affinity-mutants

    University essay from Uppsala universitet/Institutionen för farmaci

    Author : Jonathan Efverström; [2023]
    Keywords : Blood-brain barrier; In-Cell BBB-trans assay; mTfR1; Transferrin receptor; scFc-scFv8D3; Blod-hjärn barriären; mTfR1; Transferrin receptorn; scFc-scFv8D3;

    Abstract : The blood brain barrier (BBB) is a challenge when developing monoclonal antibodies for neurological diseases as antibodies do not cross the BBB making brain distribution challenging. An antibody construct which binds mTfR1 to pass the BBB, scFc-scFv8D3, have previously been developed. READ MORE

  5. 4. Recombinant expression and purification of sugar beet Phytoglobins in Escherichia Coli BL21 (DE3) including metabolic engineering of the heme biosynthesis

    University essay from Lunds universitet/Tillämpad biokemi; Lunds universitet/Beräkningskemi

    Author : Pennie Lindblom; Olivia Geel; [2023]
    Keywords : Phytoglobin; Heme; δ-ALA; qPCR; SDS-PAGE; Bacterial cultivation; Escherichia coli; BvPgb1.2; ÄKTA; Applied biochemistry; Biology and Life Sciences;

    Abstract : The protein hemoglobin (Hb) is vital for us humans to ensure enough oxygen replacement in the body. Hb-resembling proteins also exist in plants, these are called phytoglobins (Pgbs). Pgbs are very interesting since they can play a considerable role in the development of blood substitutes and iron supplements for human use. READ MORE

  6. 5. Metacaspase type II : Biochemical studies of the activation anddegradation process of calcium-independentmetacaspase type II from Arabidopsis thaliana

    University essay from Uppsala universitet/Nationellt resurscentrum för biologi och bioteknik

    Author : Anna Vikhagen; [2023]
    Keywords : ;

    Abstract : Proteases are found in all living kingdoms and are absolute essential for a functional cell to beable to break down peptide bonds. Metacaspases are proteases with the ability to cleave afterarginine and lysine residues. READ MORE