Essays about: "natural killer cells"

Showing result 1 - 5 of 14 essays containing the words natural killer cells.

  1. 1. Cytokine capture with beads in cytotoxicity assays in microwells

    University essay from KTH/Tillämpad fysik

    Author : Maxime Simon; [2023]
    Keywords : Microbead; Inteferon gamma; Natural Killer cells; microwell; binding-reaction model; Mikrokula; Interferon gamma; Naturliga Mördarceller; Mikrobrunn; modell för bindningsreaktion;

    Abstract : Cytokines are small, secreted proteins that are important for cell signalling in theimmune system. Interferon gamma (IFN-γ) is one of the most potent cytokines thatnatural killer (NK) cells of the innate immune system secrete with both antiviral,antibacterial, and antitumoral activity. READ MORE

  3. 2. The Influence of 3D Cell Organization in Tumor Spheroid on Natural Killer Cell Infiltration and Migration

    University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Author : Luigi Morrone; [2020]
    Keywords : Natural Killer Cells; Tumor Spheroids; Fluorescence Microscopy; Infiltration; Migration; Killing;

    Abstract : Natural Killer cells are a type of lymphocyte belonging to the innate immune system and they operate cell-mediated cytotoxicity and release of pro-inflammatory cytokines against cancerous cells. However, in vivo testings have shown a reduced activity of NK cells against solid tumors probably due to the negative influence of the immunosuppressive tumor microenvironment. READ MORE

  4. 3. Characterization of rituximab-induced B cell depletion and infusion reactions in a human blood loop system

    University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskap

    Author : Mikaela Zekarias; [2020]
    Keywords : Rituximab; CDC; ADCC; infusion reactions; blood loop assay; Fc engineering;

    Abstract : Introduction: Rituximab is a monoclonal antibody used to treat hematological malignancies. The antibody depletes CD20+ B cells via cytotoxic immune mechanisms, such as complement-dependent cytotoxicity (CDC) and antibody-dependent cell-mediated cytotoxicity (ADCC), which is mainly induced by natural killer (NK) cells. READ MORE

  5. 4. Oncolytic viruses armed with immunostimulatory genes for cancer treatment

    University essay from Uppsala universitet/Institutionen för immunologi, genetik och patologi; Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Mantas Šilanskas; [2018]
    Keywords : Cancer; Virus; Immunotherapy;

    Abstract : Cancer is a major health burden in modern society, costing millions of lives worldwide and negatively impacting many more. With increasing rates of cancer, there is a need for new approaches to its treatment. READ MORE

  6. 5. Canine transmissible venereal tumour

    University essay from SLU/Dept. of Anatomy, Physiology and Biochemistry

    Author : Oskar Eriksson; [2017]
    Keywords : CTVT; smittsam könstumör; hund; tumör;

    Abstract : Canine Transmissible Venereal Tumour (CTVT) är en unik smittsam tumörsjukdom. Likt en parasit är den naturligt överförbar mellan individer inom familjen Canidae via transplantation av levande tumörceller, framför allt genom parning. READ MORE