Essays about: "neurodegeneration"

Showing result 1 - 5 of 12 essays containing the word neurodegeneration.

  1. 1. Predicting tumour growth-driving interactions from transcriptomic data using machine learning

    University essay from Uppsala universitet/Neuroonkologi och neurodegeneration

    Author : Mathilda Stigenberg; [2023]
    Keywords : cancer; immunology; cell-cell interactions; deep learning; variational autoencoder; supervised variational autoencoder; tumour microenvironment; single-cell RNA sequencing; spatial transcriptomics; breast cancer; machine learning;

    Abstract : The mortality rate is high for cancer patients and treatments are only efficient in a fraction of patients. To be able to cure more patients, new treatments need to be invented. Immunotherapy activates the immune system to fight against cancer and one treatment targets immune checkpoints. READ MORE

  3. 2. Identifying cell type-specific proliferation signatures in spatial transcriptomics data and inferring interactions driving tumour growth

    University essay from Uppsala universitet/Neuroonkologi och neurodegeneration

    Author : Felix Wærn; [2023]
    Keywords : spatial transcriptomics; breast cancer; dimensionality reduction; bioinformatics; deconvolution;

    Abstract : Cancer is a dangerous disease caused by mutations in the host's genome that makes the cells proliferateuncontrollably and disrupts bodily functions. The immune system tries to prevent this, but tumours have methods ofdisrupting the immune system's ability to combat the cancer. READ MORE

  4. 3. Prediction of hub miRNAs and their associated pathways in Alzheimer's disease with miRNA-mRNA-TF network using bioinformatic tools

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Monika Kumari; [2021]
    Keywords : ;

    Abstract : The prevalence of Alzheimer’s in Europe is increasing strikingly over the past decade. Addressing this neurodegenerative disorder can be arduous as the underlying cause isn’t often reversible. READ MORE

  5. 4. Regional atrophy correlates of domain-specific episodic memory in early Alzheimer’s disease

    University essay from Lunds universitet/Institutionen för psykologi

    Author : Hannah Baumeister; [2021]
    Keywords : Alzheimer’s disease; episodic memory; amyloid-β; tau; atrophy; neurodegeneration; mnemonic discrimination; response bias; Medicine and Health Sciences;

    Abstract : Alzheimer’s disease (AD) is characterized by amyloid-β (Aβ) and tau depositions as well as neurodegeneration, and is typically accompanied by a progressive decline in episodic memory. Previous research proposes two neural memory networks that process different stimulus domains. READ MORE

  6. 5. THE NEURODEGENERATION PROCESS IN THE STRIATUM OF MICE EXPOSED TO OBESOGENIC DIETS

    University essay from Lunds universitet/Examensarbeten i molekylärbiologi

    Author : Ankita Talukdar; [2020]
    Keywords : Biology and Life Sciences;

    Abstract : Obesity and diabetes are known to impact brain function and alter metabolism. Studies in rodents show that consumption of high fat and high sugar diets lead to brain dysfunction affecting memory and cognition, and increases risk of cerebro-vascular and neurodegenerative disorders. READ MORE