Essays about: "therapeutic antibodies"

Showing result 1 - 5 of 26 essays containing the words therapeutic antibodies.

  1. 1. Development of immunoassays that can assess therapeutic bispecific antibodies on the Gyrolab platform

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Ella Hellberg; [2023]
    Keywords : ;

    Abstract : .... READ MORE

  3. 2. Effects of pharmaceutical excipients on the chemical stability of therapeutic proteins in a parenteral formulation

    University essay from Lunds universitet/Livsmedelsteknik och nutrition (master)

    Author : Emmanuel Gulangayan Deniola; [2022]
    Keywords : Chemical stability; protein degradation; GA-Z; somatropin; pharmaceutical excipients; liquid chromatography; pharmaceutical technology; Chemistry;

    Abstract : Proteins and peptides are widely used for the prevention, management, and cure of various illnesses. This vast therapeutic potential represents a significant portion of the pharmaceutical industry in the form of vaccines, antibodies, enzymes, and other protein-based therapeutics. READ MORE

  4. 3. Selection and Characterisation of Affibody Molecules Intended for Drug Conjugates Targeting Cancer Cells

    University essay from KTH/Proteinvetenskap

    Author : Elin Hedberg; [2022]
    Keywords : Affibody; AffiDC; affibody-drug conjugate; urothelial cancer; cell display; affibody library;

    Abstract : Affibodymolekyler är små affinitetsproteiner (6.5 kDa) som föreslås kunna ersätta monoklonala antikroppar i terapeutiska tillämpningsområden, exempelvis i antikropp-läkemedelskonjugat (ADCs) som kan navigera sig fram till biomarkörer som är uttryckta på cancerceller. READ MORE

  5. 4. Simulation of periodic counter-current chromatography purification of monoclonal antibodies with column degradation

    University essay from Lunds universitet/Kemiteknik (CI)

    Author : Erik Friberg; [2022]
    Keywords : Counter-current chromatography; PCC; Monoclonal antibodies; Affinity chromatography; Process control; Chemical engineering; Process simulation; Chemistry;

    Abstract : The purification process of monoclonal antibodies (mAbs) for therapeutic drugs is expensive, especially the chromatography step in which the mAbs are separated from other proteins and cells present in the feed. The antibodies are separated from the feed using affinity chromatography, where only the antibodies interact with active sites within the column, whereas the rest passes through the column without stopping. READ MORE

  6. 5. Cellular localization of the estrogen receptor GPER1 in colorectal cancer cell lines

    University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Author : Malin Lundvall; [2022]
    Keywords : colon cancer; GPER1; estrogen receptor; IF;

    Abstract : Colorectal cancer is the third most common cancer type in the world with a mortality rate of around 2000 people in Sweden, year 2018. Women tend to have a lower risk of developing and progressing colorectal cancer, specifically premenopausal women. This indicates that Estrogen plays an important role in protecting from colorectal cancer. READ MORE