Essays about: "therapeutic options"

Showing result 1 - 5 of 12 essays containing the words therapeutic options.

1. 1. Molecular mapping of the HGSOC tumour microenvironment

   University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

   Author : Philippine Louail; [2023]
   Keywords : Immunology; Ovarian cancer; Multiplex Immunofluorescence; scRNA sequencing; Bioinformatics; Image analysis;

   Abstract : High-grade serous ovarian cancer (HGSOC) is the most aggressive subtype of ovarian cancer, and its heterogeneity poses a challenge for the discovery of reliable diagnostic biomarkers, therapeutic targets, and predicting treatment response, particularly to immunotherapy. The current standard diagnostic and treatment options are inadequate, resulting in late diagnosis and poor prognosis. READ MORE

3. 2. Study of energy metabolism in fibrocytes frommyelofibrosis patients : - a comparison withhealthy individuals

   University essay from Örebro universitet/Institutionen för medicinska vetenskaper

   Author : Fanny Folkö; [2022]
   Keywords : ;

   Abstract : Introduction: Myelofibrosis is a rare and deadly disease where bone marrow fibrosisobstructs production of blood cells. Metabolic alterations in cancer cells are well researchedand considered a possible therapeutic target. Few studies have researched the same possibilityfor myelofibrosis. READ MORE

4. 3. Prehospital pain management of traumatically injured adult patients

   University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskap

   Author : Stig Benström; [2020]
   Keywords : ;

   Abstract : Title Prehospital pain management of traumatically injured adult patients Authors Benström S Institute Uppsala University, Uppsala, Sweden Background and objective Traumatic injuries are a major cause behind moderate and severe pain in a prehospital setting. Therefore, the aim of this study is to evaluate prehospital use of analgesics among adult traumatically injured patients treated within Tartu Ambulance Foundation by analysing how ambulance personnel evaluates and treats pain. READ MORE

5. 4. Exosomes and lipid nanoparticles - the future of targeted drug delivery

   University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

   Author : Sara Lundberg; Emelia Karlsson; Hugo Dahlberg; Mathilda Glansk; Sara Larsson; Sofia Larsson; Karl Carlsson; [2020]
   Keywords : Exosomes; lipid nanoparticles; drug delivery;

   Abstract : In this project an overview of how synthetic lipid nanoparticles and exosomes can be used for targeted drug delivery is compiled. The goal is to identify aspects that can be in favor for targeted drug delivery and the development of products at Cytiva. READ MORE

6. 5. Increased expression of therapeutic proteins by identification of 3'-UTRs from high expressing genes in CHO cells

   University essay from Linköpings universitet/Institutionen för fysik, kemi och biologi

   Author : Alexander Westlund; [2019]
   Keywords : Mammalian cell; CHO; E. coli; protein expression; plasmid; transformation; Fc-fusion protein; flow cytometry; FACS; transfection; mRNA; UTR; gene engineering;

   Abstract : Therapeutic proteins, a.k.a. biopharmaceuticals, are most commonly produced in expression systems derived from Chinese Hamstery Ovary (CHO) cells, thanks to great capacity of post-translational modifications like secretation, folding and glycosylation. READ MORE