Essays about: "transcriptome"
Showing result 1 - 5 of 25 essays containing the word transcriptome.
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1. EVALUATING TRANSCRIPTOME ASSEMBLY POTENTIAL BY DIFFERENT DE NOVO SEQUENCE ASSEMBLER TYPES
University essay from Högskolan i Skövde/Institutionen för biovetenskapAbstract : With the rise of NGS technologies, the transcriptomes of non-model organisms can be reconstructed even with the absence of a reference genome, using de novo assembly tools. There is a wide range of de novo assembly tools frequently being developed, however, there is a still a knowledge gap about the different effects and efficiency of different de novo assembly software types for RNA-seq assembly. READ MORE
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2. Developing Automated Cell Segmentation Models Intended for MERFISH Analysis of the Cardiac Tissue by Deploying Supervised Machine Learning Algorithms
University essay from KTH/KemiAbstract : Följande studie behandlar utvecklandet av automatiserade cellsegmenteringsmodeller med avsikt att identifiera gränser mellan celler i hjärtvävnad. Syftet är att möjliggöra analys av data genererad från multiplexed error-robust in situ hybridization (MERFISH). READ MORE
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3. Capturing genes with high impact based on reconstruction errors produced by variational autoencoders
University essay from Högskolan i Skövde/Institutionen för biovetenskapAbstract : In this work we present a novel method to extract potential hub genes, transcription factors and regions with densely interconnected protein-protein-interaction networks from RNAseq data. To achieve this we deploy variational autoencoders, a generative machine learning framework, and extract the gene-wise reconstruction errors. READ MORE
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4. Systems biology of deregulated splicing in cancer. A pan-cancer analysis of dysfunctional splicing machinery and alternative splicing events.
University essay fromAbstract : The deregulation or disruption of the splicing process has been shown to play a role in the onset, development, and even response to treatment of some malignancies. Partly due to our incomplete understanding of the mechanism and regulation behind splicing and alternative splicing, the importance of aberrant splicing in oncogenesis is not yet understood. READ MORE
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5. Detection of aberrant events in RNA for clinical diagnostics
University essay from Uppsala universitet/Institutionen för biologisk grundutbildningAbstract : Rare diseases are estimated to affect 3.75% of the global population, which roughly translates to 300 million affected individuals. READ MORE
