Essays about: "AD model mice"

Found 5 essays containing the words AD model mice.

1. 1. Characterization of biological role of FKBP51-HSP90 protein-protein interactions in novel knock-in mouse model

   University essay from KTH/Proteinvetenskap

   Author : Shaoxun Xie; [2022]
   Keywords : FK506-binding protein 51kDa; heat shock protein 90kDa; glucocorticoid signaling pathway; dexamethasone; knock-in mouse model; FK506-bindande protein 51kDa; värmechockprotein 90kDa; glucocorticoiders signalvägar; dexamethasone; knock-in musmodell;

   Abstract : Värmechockprotein 90 kDa (HSP90) bildar ett anmärkningsvärt komplicerat nätverk med en mängd olika cochaperones. Komplexet av FK506-bindande protein 51 kDa (FKBP51) och HSP90 förmedlar proteinveckning och funktion, främjar tau aggregation vid Alzheimers sjukdom och påverkar stressrelaterade störningar, fetma, typ två-diabetes, etc. READ MORE

3. 2. Födoämnesallergi hos hund : möjliga mekanismer i immunopatogenesen

   University essay from SLU/Dept. of Biomedical Sciences and Veterinary Public Health

   Author : Sandra Norrman; [2017]
   Keywords : födoämnesallergi; överkänslighet; hund; immunförsvar;

   Abstract : Många hundar med klåda och lesioner i huden lider av födoämnesallergier. Endast en liten andel av hundarna har symtom i tarmen. Patogenesen bakom dessa reaktioner och varför de ger lesioner i huden är till största del okänd. Den här litteraturöversikten sammanfattar olika möjliga mekanismer i immunopatogenesen. READ MORE

4. 3. The role of mast cells and mast cell mediators in the development of atopic dermatitis in a mouse model

   University essay from SLU/Dept. of Biomedical Sciences and Veterinary Public Health

   Author : Sofie Andersson; [2015]
   Keywords : atopic dermatitis; mouse model; mast cell; MC903; chymase; TSLP; IL - 33; atopisk dermatit; musmodell; mastcell; MC903; kymas; TSLP; IL - 33;

   Abstract : Atopic dermatitis (AD) is a complex, often lifelong allergic disease affecting around 10 % of both dogs and humans. The hallmark symptom is severe pruritus, causing a lowered quality of life. READ MORE

5. 4. Olfactory performance and neuropathology in the Tg6799 strain of Alzheimer’s disease model mice

   University essay from Institutionen för fysik, kemi och biologi

   Author : Hanna Österman; [2010]
   Keywords : 5xFAD; Alzheimer’s disease; amyloid precursor protein; amyloid β; cognitive impairment; olfactory deficit.;

   Abstract : The present study evaluated olfactory and cognitive abilities of the Tg6799 (also called 5xFAD) strain of Alzheimer’s disease (AD) model mice of two different age groups (2-3 and 8-10 months of age), and one group of healthy control mice (9-10 months). Employment of an operant conditioning paradigm using an automated olfactometer, an olfactory habituation/dishabituation test and a spatial learning test with non olfactory cues resulted in data showing that the 5xFAD mice develop olfactory impairments already at 2-3 months of age. READ MORE

6. 5. Olfactory and cognitive abilities in two strains of Alzheimer`s disease model mice

   University essay from Institutionen för fysik, kemi och biologi

   Author : Erik Boman; [2009]
   Keywords : AD model mice; tau; amyloid beta; Alzheimer`s disease; olfactory and cognitive abilities.;

   Abstract : The present study assessed olfactory and cognitive abilities in two strains of Alzheimer’s disease (AD) model mice and in healthy control mice over a four month time period. To this end an operant conditioning paradigm using an automated olfactometer and a spatial learning test with non-olfactory cues were employed and data on olfactory learning and memory, discrimination, and sensitivity as well as spatial learning and memory were collected. READ MORE