Essays about: "ATP release"

Showing result 1 - 5 of 6 essays containing the words ATP release.

1. 1. Human adenovirus type 5 infection alters mitochondrial membrane dynamics

   University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

   Author : Erik Schubert; [2021]
   Keywords : ;

   Abstract : Mitochondria are double-membrane organelles that orchestrate essential cellular functions including ATP synthesis, calcium homeostasis and apoptosis. Furthermore, mitochondria are effective stimulators of the innate immune system through the release of mitochondrial components into the cytosol. READ MORE

3. 2. The anti-amyloidogenic chaperone DNAJB6 and its interaction with other chaperones

   University essay from Lunds universitet/Matematisk statistik; Lunds universitet/Kemiska institutionen

   Author : Gemma Nilsson; [2020]
   Keywords : chaperones; DNAJB6; Hsc70; Hsp110; ATP-hydrolysis; Ab42; polyQ; biochemistry; biokemi; Chemistry;

   Abstract : In order to maintain proteins’ functionality their native folding state must be preserved. Chaperones fold other proteins and DNAJ-chaperones may collaborate with Hsc70 chaperones to prevent aggregation of aggregation-prone peptides such as polyQ and Aβ42, which form fibrils in currently incurable diseases as Huntington’s and Alzheimer’s, respectively. READ MORE

4. 3. microRNA-200 Family Expression Level Changes in Stimulated THP-1 Cells Following NLRP3 Inflammasome Activation

   University essay from Högskolan i Skövde/Institutionen för biovetenskap

   Author : Kristina Backlund; [2020]
   Keywords : ;

   Abstract : Innate immunity is the immune systems rapid responses to infection after being attacked by a pathogen. Inflammatory responses are activated by the detection of pathogen-associated molecular patterns and danger-associated molecular patterns through pattern recognition receptors on inflammatory cells. READ MORE

5. 4. Characterization of Macrophage Activation Induced by Leukotoxin from Aggregatibacter actinomycetemcomitans 

   University essay from Umeå universitet/Institutionen för odontologi

   Author : Niklas Sundling; Lisa Lü; [2018]
   Keywords : ;

   Abstract : ABSTRACT  Aggregatibacter actinomycetemcomitans (Aa), is a gram-negative, facultative anaerobe, non-motile coccobacilli colonizing the human oral cavity and is strongly associated with localized aggressive periodontitis (LAP). Aa possesses several virulence mechanisms, among others; Lipopolysaccharide (LPS), an endotoxin found in the outer membrane of Aa and Leukotoxin (LtxA), an exotoxin attached to the bacterial cell surface or in outer membrane vesicles and which has been correlating with periodontal disease mostly. READ MORE

6. 5. Effect of Aggregatibacter actinomycetemcomitans Leukotoxin on ATP Release through Pannexin Channels in Human Monocytes

   University essay from Umeå universitet/Institutionen för odontologi

   Author : Linnéa Bäck; Frykholm Jennie; [2016]
   Keywords : LtxA; ATP release; Aggregatibacter actinomycetemcomitans;

   Abstract : Aggregatibacter actinomycetemcomitans is strongly associated with aggressive periodontitis and one of several virulence factors is a leukotoxin (LtxA). The toxin has a consequential impact on human leukocytes which leads to an interference with the host ́s defences due to a chain reaction involving activation and release of a pro-inflammatory cytokine; interleukin-1β (IL-1β). READ MORE