Essays about: "ATP-binding cassette ABC transporter"

Found 3 essays containing the words ATP-binding cassette ABC transporter.

  1. 1. In silico and in vitro determination of substrate specificity for Breast Cancer Resistance Protein (BCRP) transporter at the blood-brain barrier

    University essay from Uppsala universitet/Institutionen för farmaci

    Author : Fen Wang; [2021]
    Keywords : BCRP; substrate specificity; BBB; ATP-binding cassette ABC transporter; Drug transport;

    Abstract : Background The Breast Cancer Resistance Protein (BCRP) drug transporter is important for drug disposition and plays a critical role in regulating drug entry into the brain. Its substrate spectrum overlaps with substrates of Multi Drug Resistance Protein 1 (MDR1, P-gp), which influences and complicates the interpretation of data on drug distribution into tissues (e. READ MORE

  3. 2. Mekanismer för resistens mot makrocykliska laktoner

    University essay from SLU/Dept. of Biomedical Sciences and Veterinary Public Health

    Author : Johan Sjöstedt; [2017]
    Keywords : Resistens; makrocykliska laktoner; Caenorhabditis elegans; Haemonchus contortus; Cooperia oncophora; Resistance; macrocyclic lactones;

    Abstract : Makrocykliska laktoner (ML) är ett viktig anthelmintika som används mycket. Den utbredda användningen har lett till att nematoder har utvecklat läkemedelsresistens. För att bekämpa det måste nya metoder tas fram för att hitta genetiska markörer som på ett tidigt stadie kan identifiera resistenta nematoder. READ MORE

  4. 3. Transporter protein expression and localization in murine mammary epithelial HC11 cells

    University essay from SLU/Dept. of Biomedical Sciences and Veterinary Public Health

    Author : Yagmur Yagdiran; [2012]
    Keywords : HC11cell line; mammary gland lactation; transporter proteins; Western blotting;

    Abstract : Milk is the sole food for breast-fed infants and a significant source of nutrition for consumers of dairy products. It has a very complex composition containing both macronutrients and micronutrients needed for growth and development. READ MORE