Essays about: "Adverse Drug Reaction"

Showing result 1 - 5 of 15 essays containing the words Adverse Drug Reaction.

  1. 1. Utilizing Transformers with Domain-Specific Pretraining and Active Learning to Enable Mining of Product Labels

    University essay from Uppsala universitet/Avdelningen för beräkningsvetenskap

    Author : Erik Norén; [2023]
    Keywords : Machine Learning; Natural Language Processing; NLP; BERT; Active Learning; AL; Pharmacovigilance; UMC; Uppsala Monitoring Centre; Structured Product Label; SPL; Transformers; Domain-Specific Pretraining; NER; Named Entity Recognition; Adverse Drug Reaction; ADR;

    Abstract : Structured Product Labels (SPLs), the package inserts that accompany drugs governed by the Food and Drugs Administration (FDA), hold information about Adverse Drug Reactions (ADRs) that exists associated with drugs post-market. This information is valuable for actors working in the field of pharmacovigilance aiming to improve the safety of drugs. READ MORE

  3. 2. Predicting safe drug combinations with Graph Neural Networks (GNN)

    University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskap

    Author : Amirhossein Amanzadi; [2021]
    Keywords : Drug Combination; Polypharmacy Side Effects; Graph Neural Networks;

    Abstract : Many people - especially during their elderly - consume multiple drugs for the treatment of complex or co-existing diseases. Identifying side effects caused by polypharmacy is crucial for reducing mortality and morbidity of the patients which will lead to improvement in their quality of life. READ MORE

  4. 3. Creation of a Next-Generation Standardized Drug Groupingfor QT Prolonging Reactions using Machine Learning Techniques

    University essay from Uppsala universitet/Avdelningen för systemteknik

    Author : Jacob Tiensuu; Elsa Rådahl; [2021]
    Keywords : Pharmacovigilance; Adverse Drug Reactions; MedDRA; VigiBase; WHODrug Global; QT prolongation; Torsades de Pointes; Individual Case Safety Reports; Text Recognition; Standardised Drug Grouping; Multinomial Logistic Regression; BERT;

    Abstract : This project aims to support pharmacovigilance, the science and activities relating to drug-safety and prevention of adverse drug reactions (ADRs). We focus on a specific ADR called QT prolongation, a serious reaction affecting the heartbeat. Our main goal is to group medicinal ingredients that might cause QT prolongation. READ MORE

  5. 4. Semi-supervised adverse drug reaction detection

    University essay from KTH/Skolan för elektroteknik och datavetenskap (EECS)

    Author : Louis Ohl; [2021]
    Keywords : Semi-supervised learning; Text Classification; Adverse Drug Reaction; Expectation Maximization; Natural Language Processing; Halvväglett lärande; Text klassificering; Läkemedelsrelaterade biverkningar; Naturlig språkbehandling;

    Abstract : Pharmacogivilance consists in carefully monitoring drugs in order to re-evaluate their risk for people’s health. The sooner the Adverse Drug Reactions are detected, the sooner one can act consequently. READ MORE

  6. 5. Extracting Adverse Drug Reactions from Product Labels using Deep Learning and Natural Language Processing

    University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Author : Shachi Bista; [2020]
    Keywords : ;

    Abstract : Pharamacovigilance relates to activities involving drug safety monitoring in the post-marketing phase of the drug development life-cycle. Despite rigorous trials and experiments that drugs undergo before they are available in the market, they can still cause previously unobserved side-effects (also known as adverse events) due to drug–drug interaction, genetic, physiological or demographic reasons. READ MORE