Essays about: "Alpha synuclein"

Showing result 1 - 5 of 6 essays containing the words Alpha synuclein.

  1. 1. Effect of DNAJB6 on α-synuclein amyloid fibril aggregation and dis-aggregation

    University essay from Lunds universitet/Biofysikalisk kemi

    Author : Josef Getachew; [2023]
    Keywords : α-synuclein; alpha-synuclein; chaperones; DNAJB6; the unhappy chaperone; parkinsons disease; biophysical chemistry; biochemistry; Biology and Life Sciences; Chemistry; Technology and Engineering;

    Abstract : Amyloid proteins are a group of proteins with the ability to form large fibrillar aggregates, identifiable by their cross-β core structure. These aggregates are linked to several different neurodegenerative diseases such as Parkinson’s disease and Alzheimer’s disease and due to the growing rate of people diagnosed, there is a need to combat these diseases. READ MORE

  3. 2. Affinity of Alpha-Synuclein and Lipid Vesicle Interaction

    University essay from Lunds universitet/Fasta tillståndets fysik; Lunds universitet/Fysiska institutionen

    Author : Ahmed Masaada; [2019]
    Keywords : Physics and Astronomy;

    Abstract : Alpha-synuclein is a protein involved in several neurodegenerative diseases, such as Parkinson’s, where it has been observed to form amyloid fibrils or Lewy bodies. However, how or to what extent alpha-synuclein is involved is not known. READ MORE

  4. 3. A calorimetric study of α-synuclein fibril formation & peptide induced vesicle leakage

    University essay from Lunds universitet/Kemiska institutionen

    Author : Emil Axell; [2017]
    Keywords : Differential Scanning Calorimetry; ITC; Isothermal Titration Calorimetry; Parkinson; α-synuclein; Alpha synuclein; DSC; Melittin; Vesicles; biochemistry; biokemi; Chemistry;

    Abstract : The small protein α-synuclein is strongly associated with Parkinson’s disease. This protein is found in inclusion bodies, named lewy bodies inside neurons of people suffering from the disease. α-synuclein is very abundant in the human brain, and its normal function is still elusive and unclear. READ MORE

  5. 4. Lipid Bilayers on Planes and in Micropipettes - Two model systems to study binding of DivIVA to flat and negatively curved membranes

    University essay from Lunds universitet/Fysikalisk kemi; Lunds universitet/Fysiska institutionen

    Author : Elisabeth Baumann; [2016]
    Keywords : supported lipid bilayer; DivIVA; curvature; TIRF; FRAP; epifluorescence microscopy; micropipette; model system; Physics and Astronomy;

    Abstract : The aim of this thesis work was to form and characterize model systems of cell membranes on planar supports and in micropipettes. Firstly, supported lipid bilayers (SLBs) were formed on glass slides after an existing experimental procedure. READ MORE

  6. 5. Quantification of alpha-synuclein in cerebrospinal fluid

    University essay from Institutionen för fysik, kemi och biologi; Tekniska högskolan

    Author : Björn Kronander; [2012]
    Keywords : alpha-synuclein parkinson cerebrospinal fluid biomarker;

    Abstract : To date there is no accepted clinical diagnostic test for Parkinson's disease (PD) based on biochemical analyses of blood or cerebrospinal uid. Currently, diagnosis, measurement of disease progression and response to therapeutic intervention are based on clinical observation, but the rst neuronal dysfunction precede the earliest recognition of symptom by at least 5 - 10 years. READ MORE