Essays about: "Alternativ Splicing"

Found 2 essays containing the words Alternativ Splicing.

  1. 1. Differential expression and function of fubl-1 gene isoforms in C. elegans

    University essay from Uppsala universitet/Molekylärbiologi; Uppsala universitet/Mikrobiologi och immunologi; Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Joel Pålsson; [2022]
    Keywords : isoform; gene expression; C elegans; protein; alternative splicing; isoformer; genuttryck; C elegans; protein; alternativ splicing;

    Abstract : Alternative splicing is the process of producing a variety of transcripts from one and the same gene. This adds further possible variability to gene expression and can in theory mean that one protein coding gene can produce multiple proteins with potentially different functions. READ MORE

  3. 2. Modeling the intronic regulation of Alternative Splicing using Deep Convolutional Neural Nets

    University essay from KTH/Skolan för datavetenskap och kommunikation (CSC)

    Author : Johannes Linder; [2015]
    Keywords : Machine Learning; Deep Learning; CNN; CNNs; Convolutional Neural Networks; Convolutional Neural Nets; Neural Networks; Neural Nets; Synthetic Biology; Alternative Splicing; AS; Splicing; DNA Regulation; Synthetic DNA; Massively Parallel Library; Maskinlärning; CNN; CNNs; Convolutional Neural Networks; Convolutional Neural Nets; Faltning; Neurala Nätverk; Neurala Nät; Syntetisk Biologi; Alternativ Splicing; Splicing; AS; DNA; Massivt Parallellt Bibliotek; Syntetiskt DNA;

    Abstract : This paper investigates the use of deep Convolutional Neural Networks for modeling the intronic regulation of Alternative Splicing on the basis of DNA sequence. By training the CNN on massively parallel synthetic DNA libraries of Alternative 5'-splicing and Alternatively Skipped exon events, the model is capable of predicting the relative abundance of alternatively spliced mRNA isoforms on held-out library data to a very high accuracy (R2 = 0. READ MORE