Essays about: "Amorphous drugs"

Found 2 essays containing the words Amorphous drugs.

1. 1. Fused deposition modeling of API-loaded mesoporous magnesium carbonate

   University essay from Uppsala universitet/Nanoteknologi och funktionella material

   Author : Andreas Abdelki; [2020]
   Keywords : Additive manufacturing; 3D-printing; Fused deposition modeling FDM ; Fused filament fabrication FFF ; Drug delivery; Amorphous drugs; Mesoporous magnesium carbonate; Upsalite; Cinnarizine; Hydroxypropyl cellulose HPC ; Hydroxypropyl methylcellulose acetate succinate HPMCAS ; Klucel ELF; AquaSolve LG;

   Abstract : In this thesis, the incorporation of drug loaded mesoporous magnesium carbonate as an excipient for the additive manufacturing of oral tablets by fused deposition modeling was investigated. Cinnarizine, a BCS class II drug, was loaded into the pores of the mesoporous material via a soaking method, corresponding to a drug loading of 8.68 wt%. READ MORE

3. 2. Using Upsalite® as drug delivery vehicle : Increasing the solubility of poorly soluble drugs by stabilizing their amorphous state

   University essay from Uppsala universitet/Institutionen för farmaci

   Author : Ottilia Arvén; [2017]
   Keywords : ;

   Abstract : Poor aqueous solubility is an issue not only in drug discovery and development but also for registered drug products, since poor drug solubility is often related to poor absorption (bioavailability). There are several methods available to increase the aqueous solubility and dissolution rate of pharmaceutical formulations. READ MORE