Essays about: "Amyotrofisk lateralskleros"

Found 5 essays containing the words Amyotrofisk lateralskleros.

  1. 1. Exploring IGF interactions in the context of amyotrophic lateral sclerosis

    University essay from KTH/Proteinvetenskap

    Author : Axelina Schmidt; [2023]
    Keywords : cerebrospinal fluid; plasma; insulin-like growth factors IGFs ; amyotrophic lateral sclerosis; affinity proteomics; cerebrospinalvätska; plasma; insulinliknande tillväxtfaktorer IGF ; amyotrofisk lateralskleros; affinitetsproteomik;

    Abstract : Amyotrofisk lateral skleros (ALS) är en progressiv och dödlig neurodegenerativ sjukdom som påverkar motorneuroner i både hjärnan och ryggraden. Dagens ALS forskning har ett fokus på att skapa en bättre förståelse för både sjukdomsmekanism och de metaboliska processer som bidrar till sjukdomen. READ MORE

  3. 2. Development of Sandwich Assays for Potential Protein Biomarkers in Neurodegenerative Diseases

    University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Author : Jamil Yousef; [2020]
    Keywords : Biomarkers; cerebrospinal fluid; neurodegenerative diseases; neuroproteomics; sandwich assay; suspension bead array.; Biomarkörer; ryggmärgsvätska; neurodegenerativa sjukdomar; neuroproteomik; sandwich assay; suspension bead array.;

    Abstract : As the aging population is increasing worldwide, so is the prevalence of neurodegenerativediseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD), frontotemporal dementia(FTD) and amyotrophic lateral sclerosis (ALS). Reliable biomarkers able to aid the diagnosis anddifferentiation of these diseases are needed in order to start the right treatment as early as possible. READ MORE

  4. 3. CRISPR/Cas9 gene-editing in an in vitro model of a familial form of ALS

    University essay from Lunds universitet/Tillämpad biokemi; Lunds universitet/Beräkningskemi

    Author : Fredrik Nilsson; [2018]
    Keywords : ALS; SOD1; Amyotrophic lateral sclerosis; superoxide dismutase; CRISPR Cas9; sgRNA; stem cell; lentivirus; qPCR; FOXG1; nestin; immunocytochemistry; differentiation; forebrain neural progenitor; Applied Biochemistry; Biology and Life Sciences;

    Abstract : Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease characterized by the degeneration and death of both upper and lower motor neurons for which there is no cure currently available. The degeneration of motor neurons leads to the inability to carry out voluntary movement and death usually occurs 3-5 years after disease onset by respiratory failure. READ MORE

  5. 4. Why does trehalose not improve autophagy in the SOD1G93A transgenic mouse model of familial ALS?

    University essay from SLU/Dept. of Biomedical Sciences and Veterinary Public Health

    Author : Karolina Karlsson; [2015]
    Keywords : trehalose; SOD1; amyotrophic lateral sclerosis; ALS; autophagy; plaque; neurodegeneration; trehalos; SOD1; amyotrofisk lateralskleros; ALS; autofagi; plack; neurodegeneration;

    Abstract : Amyotrophic lateral sclerosis is one of the major neurodegenerative diseases, causing an ascending paralysis that usually kills the patient within a few years from disease onset. The motor neurons show aggregates of proteins which in approximately 20 % of cases of the familial form contain mutated SOD1 protein. READ MORE

  6. 5. Livskvalitet hos personer med Amyotrofisk lateralskleros (ALS) - En litteraturstudie

    University essay from Institutionen för vårdvetenskap och sociologi

    Author : Sandra Englund; Thèrése Mårtensson; [2008]
    Keywords : Amyotrophic lateral sclerosis; ALS; quality of life; people; Amyotrofisk lateralskleros; ALS; livskvalitet; människor;

    Abstract : Syftet med denna studie var att beskriva hur människor med Amyotrofisk lateralskleros (ALS) upplever sin livskvalitet. Metoden som användes var en litteraturstudie med beskrivande design. READ MORE