Essays about: "BBB"
Showing result 1 - 5 of 21 essays containing the word BBB.
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1. Design, production and in vitro evaluation of brain shuttle scFc-scFv8D3 affinity-mutants
University essay from Uppsala universitet/Institutionen för farmaciAbstract : The blood brain barrier (BBB) is a challenge when developing monoclonal antibodies for neurological diseases as antibodies do not cross the BBB making brain distribution challenging. An antibody construct which binds mTfR1 to pass the BBB, scFc-scFv8D3, have previously been developed. READ MORE
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2. The Potential Use of Degradable Starch Microspheres as a Carrier for Nasal Drug Administration
University essay from Lunds universitet/Livsmedelsteknik och nutrition (master)Abstract : Intranasal drug delivery is a practical and accessible method for treating localized symptoms as well as achieving systemic drug absorption. The approach takes advantage of the permeability, vascularization, and limited enzymatic activity of nasal tissue, leading to enhanced drug absorption. READ MORE
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3. Sex-specific pathological response to Traumatic Brain Injury
University essay from Lunds universitet/Examensarbeten i molekylärbiologiAbstract : Traumatic brain injury (TBI) is one of leading causes of death in the world; survivors commonly exhibit behavioural changes and neurocognitive defects in the long-term. Following TBI, rapid changes in the neurovascular unit (NVU) occur as the permeability of the blood brain barrier (BBB) increases and cerebral blood flow (CBF) becomes dysregulated. READ MORE
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4. An Assessment of the Riksbank’s Corporate Bond Purchase Program on the Yield Spread and Firm’s Debt Structure
University essay from Lunds universitet/Nationalekonomiska institutionenAbstract : We study the effect of Riksbank’s corporate bond purchase program on the yield spread of bonds and firm-level debt structure. We find evidence that the Riksbank’s corporate quantitative easing announcement reduces the yield spread of eligible bonds compared to the non-eligible bonds. READ MORE
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5. Developing a Method to Study the Impact of Microbial DNA on the Brain Related to Alzheimer’s Disease – Can Food Make a Change?
University essay from Lunds universitet/Livsmedelsteknik och nutrition (master)Abstract : Understanding the gut-brain-microbiota axis can help us provide a new tool to manage conditions such as Alzheimer’s. However, a major challenge is selectively amplifying the bacterial DNA which is present at a much lower level than the host DNA. READ MORE