Essays about: "BDNF"

Showing result 1 - 5 of 6 essays containing the word BDNF.

  1. 1. When the brain loses TrkBactivation : The effects of ketamine on BDNF-TrkB neurotransmission in animal models of depression

    University essay from Linnéuniversitetet/Institutionen för kemi och biomedicin (KOB)

    Author : Hanna Sädbom-Williams; [2021]
    Keywords : Ketamine; Depression; BDNF; TrkB; Animal model; Hippocampus; Prefrontal cortex;

    Abstract : Ketamine is a non-competitive N-methyl-D-aspartate (NMDA)-channel blocker that has recently shown promise in the treatment of major depressive disorder, distinguishing itself from classical anti-depressants through its rapid and lasting effects when given at sub-anaesthetic doses. Animal models of depression are commonly used to research individual mechanisms of action and this literature review aimed to investigate how ketamine influences BDNF-TrkB neurotransmission in the hippocampus and prefrontal cortex within animal models of depression. READ MORE

  2. 2. Effects of physical and cognitive exercise on levels of peripheral BDNF in elderly : with cardiorespiratory fitness as a potential confounding factor

    University essay from Gymnastik- och idrottshögskolan, GIH/Institutionen för idrotts- och hälsovetenskap

    Author : Olga Tarassova; [2019]
    Keywords : BDNF; cardiorespiratory fitness; elderly; physical exercise; cognitive exercise;

    Abstract : .... READ MORE

  3. 3. Effects on the Hippocampal Volume and Function : Stress and Depression Versus Physical Exercise

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Emelie Olson; [2018]
    Keywords : hippocampus; hippocampal volume; hippocampal function; memory; stress; depression; physical exercise;

    Abstract : In this essay, changes in the human hippocampal volume and function induced by stress, depression and physical exercise are examined. Hippocampus is crucially involved in the acquisition and retrieval of episodic and spatial memory, and hippocampal volume correlates with episodic and spatial memory performance. READ MORE

  4. 4. Effect of voluntary exercise on BDNF/TrkB gene expression and alcohol intake.

    University essay from Institutionen för fysik, kemi och biologi; Tekniska högskolan

    Author : Josefine Jonsson; [2012]
    Keywords : Alcohol addiction; BDNF; C57BL 6 mice; Forced swim test; Gene expression; Neurotrophins; TrkB; Voluntary wheel exercise;

    Abstract : Voluntary wheel running is rewarding and believed to activate the same brain reward system as in alcohol and drug addiction. Brain-derived neurotrophic factor (BDNF), a well-known growth factor widely expressed in the brain, is modulated by both voluntary exercise and alcohol consumption. READ MORE

  5. 5. Administration of morphine and/or cocaine modulates the expression levels of genes related to plasticity mechanisms in rat hippocampus

    University essay from Institutionen för fysik, kemi och biologi

    Author : Therés Larsson; [2008]
    Keywords : ;

    Abstract : Drugs of abuse regulate the expression of several genes involved in receptor regulation and signalling, transcription factors and cytoskeleton proteins. Due to its implication in long-term memory consolidation, rat hippocampus was selected to identify genes that are differently regulated by morphine and/or cocaine administration. READ MORE