Essays about: "Bioinformatic tools"

Showing result 1 - 5 of 14 essays containing the words Bioinformatic tools.

  1. 1. Pseudomonas aeruginosa gene expression analysis using pangenome and PAO1 reference genomes

    University essay from Lunds universitet/Examensarbeten i bioinformatik

    Author : Yi Su; [2023]
    Keywords : Biology and Life Sciences;

    Abstract : Development in sequencing technologies has made the analyses of genetic material much more accessible. Processing sequenced data for an accurate analysis comes with its challenges, especially with the studies in microbial in clinical in vivo samples where difficulties in the collection of these samples for sequencing could lower the quality and contamination from the human host which might affect the accuracy of downstream analysis. READ MORE

  3. 2. Developing a reproducible bioinformatics workflow for canine inherited retinal disease

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Melina Toni Marie Martin; [2023]
    Keywords : CanFam4; Nextflow; Inherited Retinal Degeneration; dog; whole-genome sequencing; bioinformatics;

    Abstract : Inherited Retinal Degenerations (IRDs) are a heterogenous group of diseases which lead to vision impairment and can be found both in humans and in dogs. About 1 in 1,380 humans is estimated to suffer from an autosomal recessive IRD, which would be 5.5 million people worldwide, and many more are estimated to be unaffected carriers. READ MORE

  4. 3. Computational detection of human papilloma virus in the cervical cancer genome

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Hope Omoghene; [2023]
    Keywords : VirusFinder2; HPViewer; VirusSeq; HPV; Bioinformatics; Cervical cancer;

    Abstract : Global research and development have witnessed new horizons in technological advancements, especially in the use of new-generation bioinformatic tools to solve human needs. Cervical cancer, caused by a sexually transmitted virus like human papillomavirus (HPV), is one of the most common cancers threatening women's health. READ MORE

  5. 4. Immunological Cross-Reactivity : Construction of a Workflow That Enables Cross-Reactivity Predictions

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Alexander Blomlöf; Alvin Unge; Petter Byström; Erika Lindberg; Torbjörn Fries; [2022]
    Keywords : Cross- reactivity; Immunology; Epitope; Paratope; Antibody; Prediction; Substitution analysis; Proximity Extension Assay; Bioinformatic tools;

    Abstract : Cross-reactivity occurs when an antibody binds to the epitope of a protein that is not the targeted antigen. This is problematic in the analysis of immunoassay diagnostics. Detecting a protein incorrectly might cause issues such as incorrect mapping of metabolic conditions for research or diagnosis. READ MORE

  6. 5. Characterisation of structure and stability differences between the C-lobes of human and P. falciparum calmodulin in the presence of calmidazolium

    University essay from Linköpings universitet/Institutionen för fysik, kemi och biologi

    Author : Igor Blagojevic; Klara Enockson; Marcus Miras Landelius; Ylva Strid Holmertz; Emelie Weinesson; Emma Örnelöw; [2022]
    Keywords : Calmodulin; Calmidazolium; Plasmodium falciparum; Malaria; Fluorescence spectroscopy; UV spectroscopy; CD; Circular dichroism; bioinformatics;

    Abstract : Malaria is a serious disease that can lead to fatal consequences if not treated. It is mainly spread via Plasmodium falciparum, a parasite carried by mosquitoes as host organisms. As a potential way of treating malaria, research is being done on possible inhibitors of calmodulin (CaM) in the parasite. READ MORE