Essays about: "Bioinformatics"

Showing result 1 - 5 of 108 essays containing the word Bioinformatics.

  1. 1. Neural networks for imputation of missing genotype data : An alternative to the classical statistical methods in bioinformatics

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Alfred Andersson; [2020]
    Keywords : genetics; imputation; bioinformatics; neural networks; GWAS;

    Abstract : In this project, two different machine learning models were tested in an attempt at imputing missing genotype data from patients on two different panels. As the integrity of the patients had to be protected, initial training was done on data simulated from the 1000 Genomes Project. READ MORE

  2. 2. Transcriptional changes in stem cell-derived cardiomyocytes during extended cell cultures

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Michel Jonathan Speh; [2020]
    Keywords : ;

    Abstract : The recent advancement in the field of stem cell research gave rise to high expectations from both general and scientific audiences, and indeed, stem cells and stem cell-derived cells have an enormous potential to forward the fields of medical research and regenerative medicine. Nevertheless, there are still many obstacles and limitations associated with stem cell technology. READ MORE

  3. 3. Dual RNA-seq analysis of host-pathogen interaction in Eimeria infection of chickens

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Arnar Kári Sigurðarson Sandholt; [2020]
    Keywords : Dual RNA-seq; Bioinformatics; Eimeria tenella; Gene co-expression networks; Chicken;

    Abstract : Eimeria tenella is a eukaryotic, intracellular parasite that, along with six other Eimeria species, causes coccidiosis in chickens. This disease can result in weight loss or even death and is estimated to cause 2 billion euros of damages to the chicken industry each year. While much is known of the life cycle of E. READ MORE

  4. 4. Analysis of differentially expressed genes (DEGs) in neuronal cells from the cerebral cortex of Alzheimer’s disease mouse model

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Elnaz Bakhtiyari; [2020]
    Keywords : ;

    Abstract : Alzheimer’s disease (AD) is an aging-related neurodegenerative disorder with large implications for society and individuals. AD is a multi-factor disorder, with these factors having a direct or indirect correlation with each other. READ MORE

  5. 5. Causality in Coexpression

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Carolina Barros; [2020]
    Keywords : bioinformatics; computational biology; genomics; causality; genetics; coexpression;

    Abstract : One of the main goals of genetics has been to understand the link between genotype and phenotype. Using yeast (Saccharomyces cerevisiae) as our model organism, we take a closer look at the connection between genetic variation and gene expression to learn more about the mechanisms of gene regulation. READ MORE