Essays about: "Bioinformatik"

Showing result 1 - 5 of 24 essays containing the word Bioinformatik.

  1. 1. Big Data Workflows: DSL-based Specification and Software Containers for Scalable Execution

    University essay from KTH/Skolan för elektroteknik och datavetenskap (EECS)

    Author : Yared Dejene Dessalk; [2020]
    Keywords : Big Data workflow; Domain-specific language; Software container; Message­ oriented middleware; Scalable execution; Big Data-arbetsflode; Doman-specifikt sprak; Programvarubehallare; Meddelande-orienterad mellanprogramvara; Skalbar korning;

    Abstract : Big Data workflows are composed of multiple orchestration steps that perform different data analytics tasks. These tasks process heterogeneous data using various computing and storage resources. READ MORE

  2. 2. Whole-Genome Sequencing of two Swedish Individuals on PromethION

    University essay from Lunds universitet/Examensarbeten i bioinformatik

    Author : Nazeefa Fatima; [2019]
    Keywords : Biology and Life Sciences;

    Abstract : Background: Chromosomes can undergo various changes such as deletions, inversions, insertions, and/or translocations resulting in structural variation differences between individuals. Structural variants are a common source of variability in the human genome and have been known to be associated with common diseases such as autism, cancer, and rare human diseases [1, 2]. READ MORE

  3. 3. Validation of a new software for detection of resistance associated substitutions in Hepatitis C-virus

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Caitlin Vigetun Haughey; [2019]
    Keywords : Hepatitis C virus; HCV; Resistance; NS5A; Resistance associated substitutions; RAS; PacBio sequencing; Bioinformatics; Hepatit C virus; HCV; Resistens; NS5A; Sekvensering; PacBio; Bioinformatik;

    Abstract : Hepatitis C infection is a global disease that causes an estimated 399,000 deaths per year. Treatment has improved dramatically in recent years through the development of direct acting antivirals that target specific regions of the Hepatitis C virus (HCV). READ MORE

  4. 4. Modifying a Protein-Protein Interaction Identifier with a Topology and Sequence-Order Independent Structural Comparison Method

    University essay from Linköpings universitet/Bioinformatik

    Author : Joakim Johansson; [2018]
    Keywords : PPI; Protein-protein interaction; Machine learning; Protein modelling; Structural bioinformatics; Structural alignment; Sequence-order independent;

    Abstract : Using computational methods to identify protein-protein interactions (PPIs) supports experimental techniques by using less time and less resources. Identifying PPIs can be made through a template-based approach that describes how unstudied proteins interact by aligning a common structural template that exists in both interacting proteins. READ MORE

  5. 5. SVenX: A highly parallelized pipeline for structural variation detection using linked read whole genome sequencing data

    University essay from Lunds universitet/Examensarbeten i bioinformatik

    Author : Vanja Börjesson; [2018]
    Keywords : Biology and Life Sciences;

    Abstract : Genomic rearrangements larger than 50 bp are called structural variants. As a group, they affect the phenotypic diversity among humans and have been associated with many human disorders including neurodevelopmental disorder and cancer. READ MORE