Essays about: "Biologics"

Showing result 1 - 5 of 11 essays containing the word Biologics.

1. 1. OPTIMIZATION OF CLONE SELECTION PLATFORM FOR PRODUCTION OF RECOMBINANT PROTEINS

   University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

   Author : Basel Yousef; [2024]
   Keywords : ;

   Abstract : Background  Biologics are type of proteins that can be produced by expression in a foreign host for medical healthcare applications in humans. Monoclonal antibodies (mAbs) are type of biologics that are designed to specifically bind to one target, with a purpose to inhibit a certain molecule that could be associated with a disease process. READ MORE

3. 2. Förekomst av bandmask hos föl i Mälardalen : en jämförelse mellan koprologisk och serologisk diagnostik

   University essay from SLU/Dept. of Biomedical Sciences and Veterinary Public Health

   Author : Elvira Nordin; [2024]
   Keywords : Anoplocephala; Cestoder; Prevalens; Häst; Ekvin; ELISA; Flotation;

   Abstract : Anoplocephala perfoliata är den vanligaste bandmasken som hästar infekteras av och infektion med cirka 20 bandmaskar eller fler kan orsaka kolik. Förekomsten av bandmask hos vuxna hästar har studerats i många länder och prevalensen har varierat, i Sverige har undersökningar visat prevalenser mellan 3–65 % vilket bland annat är beroende av analysmetoden. READ MORE

4. 3. Developing and validating assay-ready HEK-Blue CD40L cells : For a more flexible and faster screening of Affibody® molecules

   University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskap

   Author : Erika Könberg; [2022]
   Keywords : cell biology; assay-ready cells; HEK-Blue cells;

   Abstract : Cell assay that evaluates a biologics’ potency and efficacy is an important part in the discovery and development of drug candidates. However, it requires regular maintenance of cell cultures, and the cell assays can only be performed when the cells have reached 70-80% confluency. READ MORE

5. 4. Quality and Regulatory Issues Related to Continuous Manufacturing of Biologics

   University essay from Lunds universitet/Livsmedelsteknik och nutrition (master)

   Author : Sorosh Ziarati; [2022]
   Keywords : Continuous Manufacturing; Regulation; Continuous freeze drying; Biopharmaceutical; Trastuzumab; Pharmaceutical Technology; Technology and Engineering;

   Abstract : Introduction: Continuous Manufacturing involves the continuous feeding of input materials into the transformation of in-process materials within, and the concomitant removal of output materials from a manufacturing process based on ICH guideline. In these systems, all the processes from raw material to final finished product would be continuously produced. READ MORE

6. 5. Aggregation mechanisms of proteins in liquid formulations

   University essay from KTH/Kemi

   Author : Amanda Hamrin; [2022]
   Keywords : Protein aggregering; seedingmekanism; dynamic light scattering; differential scanning calorimetry; Somatropin; monoklonal antikropp; Protein aggregation; seeding mechanism; dynamic light scattering; differential scanning calorimetry; somatropin; monoclonal antibody;

   Abstract : Biologiska läkemedel har under det senaste århundradet utökats, och under de senaste 25 åren så har proportionen av godkända biologiska läkemedel har ökat för behandlingen av sjukdomar, vaccin, och diagnostik. Det finns flera olika mekanismer för protein aggregering, och en av dessa är seeding, vilket innebär aggregering inducerat av tillsatta aggregat eller förekomsten av strukturförändringar i proteinet. READ MORE