Essays about: "Biopharmaceuticals"

Showing result 11 - 15 of 18 essays containing the word Biopharmaceuticals.

  1. 11. Antibiotic free and optimised protein production using Escherichia coli

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Mathias Engström; Olle Pontén; Carlsson Philip; Nadeen Bahnam; Ella Strömberg; Oskar Westlin; [2018]
    Keywords : TAT; recombinant protein production; optimisation; fermentation; chromatography; protein purification; filtration; excretion system; affibody; biopharmaceuticals; validation;

    Abstract : Affibody® molecules are small therapeutic proteins which mimics antibody functionality. This is a report of several methods for increasing productivity and yield in recombinant production of Affibody® molecules. READ MORE

  3. 12. Antibody drug conjugates (ADC) : Current status and mapping of ADC:s in clinical programs

    University essay from Uppsala universitet/Institutionen för teknikvetenskaper

    Author : Samantha Congreve; Reham Faris Elias; Gabriel Tidestav; Venus Zafranian; [2018]
    Keywords : ADC; antibody; drug; conjugate; biopharmaceuticals; structure; linker; payload; target; conjugation; market;

    Abstract : A literature study was performed on a new type of cancer medicine: antibody drug conjugates, or ADCs. These consist of a monoclonal antibody, chemically linked to a cytotoxic agent. What makes them unique is their selective toxicity against cancer cells. READ MORE

  4. 13. A Model-based Approach to Evaluating Chromatography Capture Steps

    University essay from Lunds universitet/Kemiteknik (CI)

    Author : Jakob Ulmestig; [2017]
    Keywords : Periodic counter-current chromatography; PCC; Continuous chromatography; Continuous bioprocessing; Sequential capture; Model based optimization; Breakthrough curve; chemical engineering; kemiteknik; Technology and Engineering;

    Abstract : Recent advances in upstream production of biopharmaceuticals have not yet been matched by equivalent advances in the downstream processing. As chromatography is currently the primary downstream processing method in production of biopharmaceuticals new methods for multicolumn processes are being developed. READ MORE

  5. 14. Unwanted Side-Effects: Idiosyncratic Volatility and M&A Activity in the U.S. Biopharmaceuticals Industry

    University essay from Handelshögskolan i Stockholm/Institutionen för finansiell ekonomi

    Author : Ceilidh Meagher; Anton Truvé; [2016]
    Keywords : Pharmaceuticals; Biotech; Volatility; M A; Timeseries;

    Abstract : In this paper we use the disaggregated approach as outlined by Campbell et al. (2001) to study the volatility of firms within the U.S. pharmaceutical and biotech industry at the market, industry and firm levels. READ MORE

  6. 15. Performance analysis of a PEGylation process -Process comparison of a tubular reactor with recirculation to a conventional batch reactor

    University essay from Lunds universitet/Kemiteknik (CI)

    Author : Boris Torbica; [2015]
    Keywords : Ion Exchange Chromatography; Recirculation; Tubular reactor; Tube reactor; PEGylation; PEG Polyethylene glycol; IEC; Optimisation; Chemical Engineering; kemiteknik; Technology and Engineering;

    Abstract : Since the rise of therapeutical proteins, there has been a growing interest in biopharmaceuticals over the years. Research was made to combat various protein weaknesses like fast degradation and low solubility. A discovery in the 1970s suggested that an attachment of polyethylene glycol (PEG) on protein surfaces would solve the specific problems. READ MORE