Essays about: "CRISPR Cas9"

Showing result 11 - 15 of 50 essays containing the words CRISPR Cas9.

  1. 11. Novel mRNA therapeutics for cardiomyogenesis and vasculogenesis

    University essay from KTH/Proteinvetenskap

    Author : Xiaoting Huang; [2022]
    Keywords : Heart; Placental growth factor PLGF ; Cardiomyogenesis; Vasculognesis; Regeneration; hjärta; PLGF; kardiomyogenes; vaskulogenes; regenerering;

    Abstract : Kardiovaskulära sjukdomar är fortfarande en av de främsta dödsorsakerna i dag. Den främsta orsaken till sjukdomen är skador på hjärtcellerna, som kanske inte kan repareras av sig själva, så att utveckla en ny terapi för att regenerera eller reparera hjärtcellerna är ett viktigt mål inom forskningen om hjärtsjukdomar. READ MORE

  3. 12. Generation of induced pluripotent stem cells (iPSCs) lines deficient for genes associated with neurodevelopmental diseases using CRISPR/Cas9 technology

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Claudia De Guidi; [2021]
    Keywords : ;

    Abstract : Induced pluripotent stem cells (iPSCs) can self-renew and differentiate into many other cell types. IPSCs are derived from somatic cells, and upon reprogramming, they share an expression profile similar to embryonic stem cells (ESCs). READ MORE

  4. 13. Potential Application of Multiplex Automated Genome Engineering (MAGE) and One-Step Curing Plasmid System for Environmental Cambodian Enterobacterial Isolates

    University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Author : Olivia Alexandra; [2021]
    Keywords : Antimicrobial resistance; plasmid curing; environmental isolates; recombineering; enterobacteria;

    Abstract : Antimicrobial resistance (AMR) is concerning because it limits antimicrobial drug treatment options. AMR occurs by the overuse and misuse of antimicrobial drugs. In environmental settings, AMR can disseminate from places of high use, which leads to increased exposure to humans and animals. READ MORE

  5. 14. The use of a CRISPR-Cas9 system to protect probiotic strains from transferrable drug resistance genes

    University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Author : Sara Lundberg; [2021]
    Keywords : CRISPR-Cas9; antibiotic resistance; horizontal gene transfer; probiotic bacteria;

    Abstract : The discovery of antibiotics have revolutionized modern medicine, facilitating the treatment of a variety of bacterial infections, enabled surgeries otherwise impossible to perform and increased life expectancy in all countries. However, the rapid development of resistance among microorganisms and the increasing numbers of clinical outbreaks caused by multiresistant bacteria have accelerated the need for new alternatives to antibiotics. READ MORE

  6. 15. Visualizing neuronal cell sub-populations using novel transgenic zebrafish lines.

    University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Author : Aikaterini Zafeiriou; [2021]
    Keywords : Zebrafish; CRISPR Cas9; locomotion; confocal microscopy; immunohistochemistry;

    Abstract : Zebrafish is a frequently used model organism with an array of transgenic lines that have been used indevelopmental and physiological studies. We aim to generate novel transgenic zebrafish reporter lines to study subpopulations of spinal neurons in vivo. READ MORE