Essays about: "CYP"

Found 5 essays containing the word CYP.

  1. 1. An in vitro model for studying gene expression in Parascaris univalens larvae

    University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Author : Sofia Jonsson; [2019]
    Keywords : Parascaris univalens; equine roundworm; Parascaris; Parascaris univalens larvae; anthelmintic resistance; drug metabolism; gene expression; in vitro model; ivermectin.;

    Abstract : Parascaris univalens, equine roundworm, is a large nematode infecting young horses and causes respiratory syndromes, impaired condition and reduced growth. Adults can reach up to 50 cm in length and heavy infection can lead to obstruction and rupture of the small intestines due to the worm’s size. READ MORE

  3. 2. Impact of maternal smoking onmRNA expression in placental tissue : - a systematic literature survey

    University essay from Örebro universitet/Institutionen för medicinska vetenskaper

    Author : Felix Roxenlund; [2019]
    Keywords : ;

    Abstract : Introduction: Maternal smoking during pregnancy is becoming less common. However, it is still a significant predictor of adverse outcomes. Smoking during pregnancy has been associated with impaired fetal development and growth. READ MORE

  4. 3. Cytokrom P450-systemets betydelse för anthelmintikaresistens

    University essay from SLU/Dept. of Biomedical Sciences and Veterinary Public Health

    Author : Ylva Lagervall; [2013]
    Keywords : anthelmintika; resistens; cytokrom; CYP; P450; helminter; inhibering;

    Abstract : Läkemedelsresistenta parasiter är ett allvarligt globalt problem. Läget är framför allt kritiskt inom gruppen gastrointestinala nematoder hos små idisslare, vilka ofta uppvisar resistens mot bredspektrumverkande anthelmintika. Resistensproblematiken resulterar i en försämrad djurvälfärd och lägre produktionsnivåer. READ MORE

  5. 4. Molecular analysis of insecticide resistance in pollen beetle (Meligethes aeneus)

    University essay from SLU/Dept. of Plant Biology and Forest Genetics (until 131231)

    Author : Jessica Pernestål; [2009]
    Keywords : Pyrethroid; resistance; voltage-sensitive sodium channel VSSC ; cytochrome P450; pollen beetle; Meligethes aeneus;

    Abstract : The escalating usage of pyrethroids has resulted in an increased awareness about resistance towards pyrethroids in insects. Pyrethroids inhibit voltage-sensitive sodium channels (VSSC) in nerve cell membranes and are composed of synthetic molecules based on pyrethrins present in pyrethrum extracts from Chrysanthemum species. READ MORE

  6. 5. Development of an assay for screening drug candidates for mechanism-based inhibition of human CYP3A4

    University essay from Institutionen för livsvetenskaper

    Author : Maria Khihon Rokhas; [2008]
    Keywords : ;

    Abstract : Cytochrome P450 (CYP) constitutes a superfamily of heme- containing enzymes that catalyze the oxidative biotransformation of structurally diverse xenobiotics including pharmaceuticals and drugs. Cytochrome P450 3A4 is not only the most abundant isoform in human liver but is also responsible for metabolizing approximately 60% of therapeutic drugs. READ MORE