Essays about: "Cancer sequencing"

Showing result 16 - 20 of 57 essays containing the words Cancer sequencing.

  1. 16. System level analysis of Immune system in children with solid tumors

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning; Uppsala universitet/Science for Life Laboratory, SciLifeLab

    Author : Nadia Hassan Shamas; [2022]
    Keywords : Immune system in Children; Cancer; Medicines;

    Abstract : Over the last few years, significant immune system changes have been observed in tumor patients exposed to different treatments. Moreover, evaluation and prediction of the responses of treatments given to these patients can become a key component. READ MORE

  3. 17. Filtering of Clinical NGS Data to Improve Low Allele Frequency Variant Calling

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Tomas Cumlin; [2022]
    Keywords : Next-generation sequencing; Variant calling; Clinical sequencing; Substitution error; Cancer sequencing; Error rate; substitution; Somatic mutation;

    Abstract : Massive parallel sequencing (NGS) is useful in detecting and later classifying somatic driver mutations in cancer tumours. False-positive variants occur in the NGS workflow and they may be mistaken for low frequency somatic cancer mutations in a patient sample. READ MORE

  4. 18. An explorative study of gene expression of relevance to T cells and cancer

    University essay from KTH/Proteinvetenskap

    Author : Nagham Saleh; [2022]
    Keywords : CAR T-cells; ScRNA-seq; Cytokine; Differentiation; Scanpy; CAR T-celler; ScRNA-seq; Cytokin; Differentiering; Scanpy;

    Abstract : Cancer är den näst mest förekommande dödsorsaken i världen följt av hjärt- och kärlsjukdomar. De mest använda cancer behandlingar såsom kemoterapi är inte tillräckligt effektiva och specifika mot cancer då de även attackerar normala celler och ger upphov till flertal bieffekter. Således har immunoterapier såsom t.ex. READ MORE

  5. 19. Affibody phage display selections for lipid nanoparticle and affibody-mediated transient CAR T-cell therapy

    University essay from KTH/Proteinvetenskap

    Author : Tasnim Yasin Idris; [2022]
    Keywords : affibody; phage display; in vitro selection; CD5; CD8; CD19; CAR T-cell therapy.;

    Abstract : CAR T-cellbehandling är en immunterapi som har visat lovande resultat vid behandling av cancer. Trots det riktade immunsvaret som kan uppnås, betonar komplexiteten i tillverkningsprocessen och behandlingsproceduren det utrymme somm finns för förbättringar. READ MORE

  6. 20. Systems biology of deregulated splicing in cancer. A pan-cancer analysis of dysfunctional splicing machinery and alternative splicing events.

    University essay from

    Author : Leticia Castillon; [2021-08-06T14:57:24Z 2021-08-06T14:57:24Z 2021 2020]
    Keywords : multi-omics; splicing; alternative splicing; deep learning; cancer; transcriptome;

    Abstract : The deregulation or disruption of the splicing process has been shown to play a role in the onset, development, and even response to treatment of some malignancies. Partly due to our incomplete understanding of the mechanism and regulation behind splicing and alternative splicing, the importance of aberrant splicing in oncogenesis is not yet understood. READ MORE