Essays about: "Cancer therapeutics"

Showing result 1 - 5 of 11 essays containing the words Cancer therapeutics.

  1. 1. Generation of a new ADAPT library for stability improvement

    University essay from KTH/Proteinvetenskap

    Author : Sumant Yogesh Salphale; [2023]
    Keywords : Phage display; CEACAM5; EpCAM; Trop2; ADAPT; ABD; protein engineering; cancer detection; Fag-display; CEACAM5; EpCAM; Trop2; ADAPT; ABD; proteinteknik; cancerdetektion;

    Abstract : Under senare år har målinriktad terapi varit ett växande område inom cancerterapi som en mer målinriktad behandling än kemoterapi. Dessa behandlingar baseras främst på antikroppsbaserade läkemedel som är ganska stora och komplexa, vilket ökar den totala kostnaden för behandlingen. READ MORE

  3. 2. Effects of pharmaceutical excipients on the chemical stability of therapeutic proteins in a parenteral formulation

    University essay from Lunds universitet/Livsmedelsteknik och nutrition (master)

    Author : Emmanuel Gulangayan Deniola; [2022]
    Keywords : Chemical stability; protein degradation; GA-Z; somatropin; pharmaceutical excipients; liquid chromatography; pharmaceutical technology; Chemistry;

    Abstract : Proteins and peptides are widely used for the prevention, management, and cure of various illnesses. This vast therapeutic potential represents a significant portion of the pharmaceutical industry in the form of vaccines, antibodies, enzymes, and other protein-based therapeutics. READ MORE

  4. 3. 3′-end fluorescence labelling of long RNAs using terminal deoxynucleotidyl transferase

    University essay from Lunds universitet/Kemiska institutionen

    Author : Johannes Lidberg; [2022]
    Keywords : Physical biochemistry; Fluorescence; In vitro transcription; RNA; Terminal deoxynucleotidyl transferase; Nucleobase analogue; Chemistry;

    Abstract : Through recent years, RNA has rapidly gone from mainly being known as a passive information-carrying molecule within the central dogma of molecular biology to becoming the active ingredient in multiple therapeutics, such as in vaccines and potential drugs against cancer. However, one of the main challenges with RNA as a therapeutic is efficient delivery to cells. READ MORE

  5. 4. ProTargetMiner one step further : Deep comparative proteomics of Dying vs. Surviving cancer cells treated with anticancer compounds

    University essay from Uppsala universitet/Analytisk kemi

    Author : Albin Lundin; [2022]
    Keywords : Cancer; Surviving VS Dying; Proteomics; Comparative Proteomics; RKO; A549; MCF7; drug discovery; life; death; life and death decisions; target ranking; OPLS-DA; drug targets; novel anticancer agents;

    Abstract : Cancer is a leading cause of mortality worldwide, responsible for nearly one in six deaths. Thus, there is a need for a greater understanding of cancer for the development of novel therapeutics. This master thesis project aims to compare the proteome signatures between dying and surviving cancer cells treated with diverse anticancer drugs. READ MORE

  6. 5. An explorative study of gene expression of relevance to T cells and cancer

    University essay from KTH/Proteinvetenskap

    Author : Nagham Saleh; [2022]
    Keywords : CAR T-cells; ScRNA-seq; Cytokine; Differentiation; Scanpy; CAR T-celler; ScRNA-seq; Cytokin; Differentiering; Scanpy;

    Abstract : Cancer är den näst mest förekommande dödsorsaken i världen följt av hjärt- och kärlsjukdomar. De mest använda cancer behandlingar såsom kemoterapi är inte tillräckligt effektiva och specifika mot cancer då de även attackerar normala celler och ger upphov till flertal bieffekter. Således har immunoterapier såsom t.ex. READ MORE