Essays about: "Cancer therapy"

Showing result 1 - 5 of 191 essays containing the words Cancer therapy.

  1. 1. Apoptosis induction in breast cancer cells after radiotherapy and potential radiosensitizers

    University essay from

    Author : Klara Simonsson; [2023-06-27]
    Keywords : Medical physics; Breast cancer cells; radiotherapy; systemic therapy; combination therapy; apoptosis; BH3 profiling; flow cytometry;

    Abstract : Background. Today breast cancer is the foremost cancer death type amongst women around the world. At present some of the toughest challenges in the clinic is recurrent, radioresistant breast cancer, and metastatic breast cancer where low cure rates are observed after surgery and radiotherapy. READ MORE

  3. 2. Uncertainty Estimation in Radiation Dose Prediction U-Net

    University essay from KTH/Skolan för elektroteknik och datavetenskap (EECS)

    Author : Frida Skarf; [2023]
    Keywords : Radiation dose prediction models; U-net; quantile regression; Monte Carlo Dropout; epistemic uncertainty estimation; aleatoric uncertainty estimation; Stråldospredicerande modeller; U-net; kvantilregression; Monte Carlo Dropout; epistemisk osäkerhetsskattning; aletorisk osäkerhetsskattning;

    Abstract : The ability to quantify uncertainties associated with neural network predictions is crucial when they are relied upon in decision-making processes, especially in safety-critical applications like radiation therapy. In this paper, a single-model estimator of both epistemic and aleatoric uncertainties in a regression 3D U-net used for radiation dose prediction is presented. READ MORE

  4. 3. Comparison of psychedelic therapies versus placebo in the treatment of psychiatric illnesses: a systematic review of randomized trials including placebo controls

    University essay from Lunds universitet/Institutionen för psykologi

    Author : Aleksandra Barbara Barstowe; [2023]
    Keywords : psychedelic-assisted therapy; placebo; psychiatric illness; psykedelisk-assisterad terapi; psykiatrisk sjukdom; Social Sciences; Medicine and Health Sciences;

    Abstract : Psychedelics have long been recognized for their powerful effects on the human psyche and psychedelic-assisted therapy is becoming increasingly acknowledged as an effective therapeutic intervention. Placebos are used in clinical research to validate the efficacy of a therapy or treatment. READ MORE

  5. 4. Development of a PNA-drug conjugate for pretargeted delivery of cytotoxic drugs

    University essay from Uppsala universitet/Theranostics

    Author : Astrid Haraldsson; [2023]
    Keywords : PNA; pretargeting; cancer therapy; cytotoxic payload;

    Abstract : One of the major challenges in cancer treatment is delivering high enough doses of active substance specifically to cancer cells without accumulation in healthy organs. Pretargeting has emerged as a potential solution, where the delivery of a cancer recognizing (primary) agent and a cancer killing (secondary) agent are separated. READ MORE

  6. 5. Combining doxorubicin and gemcitabine with targeted drugs as a treatment option for high-risk neuroblastoma

    University essay from KTH/Proteinvetenskap

    Author : Alexandra Johannesson; [2023]
    Keywords : neuroblastoma; doxorubicin; gemcitabine; targeted drugs; ATM; neuroblastom; doxorubicin; gemcitabin; målinriktade läkemedel; ATM;

    Abstract : Neuroblastom är en barncancer som uppstår ur det sympatiska nervsystemet och drabbar omkring 15 barn i Sverige varje år. Högriskvarianten är associerad med mycket hög dödlighet och risk för återfall, vilket tros ha att göra med att tumörernas ovanligt heterogena sammansättning tillåter resistenta subpopulationer att motstå konventionella behandlingsmetoder. READ MORE