Essays about: "Chk1"

Found 2 essays containing the word Chk1.

  1. 1. Investigation of drug-induced cell cycle responses in high-risk neuroblastoma

    University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Author : Maryam Sahi; [2020]
    Keywords : Neuroblastoma; chemotherapy resistance; cell cycle arrest; cisplatin; doxorubicin; ATM; Chk1; Wee1; Neuroblastom; kemoterapiresistans; cellcykelarrest; cisplatin; doxorubicin; ATM; Chk1; Wee1;

    Abstract : The childhood cancer neuroblastoma mostly affects children under the age of 2 and comprises 6% of all childhood cancers. Neuroblastoma has very diverse phenotypes caused by both inter- and intra-tumour heterogeneities. The phenotypes are classified as being either low- or high-risk. READ MORE

  3. 2. Mapping the Expression of Cyclin Dependent Kinase Inhibitors in High-Risk Neuroblastoma Cell Lines : Dynamics on Cell-Fate Decisions on Proliferation/Cell Cycle Arrest

    University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Author : Ximena López Lorenzo; [2020]
    Keywords : Neuroblastoma; NMYC; p53; cell cycle checkpoint; inhibition; regrowth; p21; p27; SKP2; CHK1 2; Neuroblastoma; NMYC; p53; cellcykel checkpoint; hämning; återväxt; p21; p27; SKP2; CHK1 2;

    Abstract : Poor prognosis for high-risk neuroblastoma patients makes it necessary to find novel treatmentstrategies. This work aims to understand the cell cycle behavior of various high-riskneuroblastoma cell lines following chemotherapy treatment. READ MORE