Essays about: "Clinical sequencing"

Showing result 21 - 25 of 47 essays containing the words Clinical sequencing.

  1. 21. Supervised Learning for Prediction of Tumour Mutational Burden

    University essay from KTH/Matematisk statistik

    Author : Joanna Hargell; [2021]
    Keywords : Supervised Learning; Tumour Mutational Burden; Generalized Linear Models; Decision trees; Support Vector Machines; statistik; tillämpad matematik; statistisk inlärning; mutationsbörda;

    Abstract : Tumour Mutational Burden is a promising biomarker to predict response to immunotherapy. In this thesis, statistical methods of supervised learning were used to predict TMB: GLM, Decision Trees and SVM. READ MORE

  3. 22. Next-generation diagnostics of escherichia coli from community-onset sepsis patients in sweden : Studying the biodiversity of escherichia coli genomes

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Nada Mahmoud; [2021]
    Keywords : ;

    Abstract : Escherichia coli (E. coli) is among the gram-negative bacteria that can cause several infections including sepsis. Confirmed sepsis patients must show a sequential organ failure assessment (SOFA) score of ≥2 with verified infection. Understanding the genotypic characteristics of E. READ MORE

  4. 23. Evaluation of the Oxford Nanopore Minion for the identification and differentiation of MRSA and non-MRSA isolates

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Kristoffer Nilsson Grimstad; [2020]
    Keywords : ;

    Abstract : Staphylococcus aureus are bacterial pathogens causing infectious diseases. Methicillin-resistant S. aureus, or MRSA, carry the mecA or mecC genes generating resistance to β-lactam antibiotics. MRSA is problematic to treat and crucial to rapidly detect while current diagnostic workflows are time-consuming. READ MORE

  5. 24. Characterization of infectious laryngotracheitis virus from outbreaks in Swedish chicken hobby flocks

    University essay from SLU/Dept. of Clinical Sciences

    Author : Liv Jonare; [2020]
    Keywords : backyard flocks; chickens; infectious laryngotracheitis; virus; vaccine; coinfections; latency; sequencing; complete genome sequencing; PCR; non-commercial poultry;

    Abstract : Infectious laryngotracheitis (ILT) is a respiratory tract infection of gallinaceous birds, which is caused by Gallid herpes virus 1 (GaHV-1), also called infectious laryngotracheitis virus (ILTV). In its most virulent form it can cause acute respiratory symptoms such as marked dyspnoea, gasping, expectoration of bloody mucus, high mortality (up to 70%) and production losses, such as decreased growth and egg production. READ MORE

  6. 25. Detection of hotspot mutations in IDH1/2 in patients withacute myeloid leukemia using Droplet Digital PCR

    University essay from Örebro universitet/Institutionen för medicinska vetenskaper

    Author : Johanna Wågberg; [2020]
    Keywords : AML; IDH1; IDH2; ddPCR; NGS;

    Abstract : IntroductionAcute myeloid leukemia (AML) is caused by a wide range of genetic aberrations, includingmutations within the genes that encode the enzymes isocitrate dehydrogenase 1 and 2(IDH1/2). Drugs that target mutant IDH1/2 are now available, which makes assessment of themutational status of IDH1/2 important in clinical diagnostics of AML. READ MORE