Essays about: "Clinical trials"

Showing result 1 - 5 of 99 essays containing the words Clinical trials.

  1. 1. Design and analysis of pre-clinical experiments using a method combining multiple comparisons and modeling techniques for dose-response studies

    University essay from Göteborgs universitet/Institutionen för matematiska vetenskaper

    Author : Avijit Singh; [2021-04-20]
    Keywords : pharmacodynamic modeling; dose–response relationship; significance level; multiple comparison procedure; optimal design; MCPMod; dose finding study;

    Abstract : Abstract. Identifying and estimating the dose-response relationship between a compound anda pharmacological endpoint of interest is one of the most important and difficult goals in thepreclinical stage of pharmaceutical drug development. READ MORE

  2. 2. Formulation development of a recombinant VAR2-antiCD3 protein for cancer immunotherapy

    University essay from Lunds universitet/Livsmedelsteknik och nutrition (master)

    Author : Maja Warlin; Frida Hallberg; [2021]
    Keywords : immunotherapy; cancer; pharmaceuticals; proteins; analytical techniques; molecular biotechnology; formulation; life science; engineering; pharmaceutical technology; Technology and Engineering;

    Abstract : The use of immunotherapy for treating cancer has received a lot of attention in the recent years. The therapy is based on activating or deactivating the patient’s own immune system to help fight the disease. One way of doing this, is using bispecific molecules that can target both cancer cells and T-cells simultaneously. READ MORE

  3. 3. Treating latent tuberculosis : Efficacy of rifapentine plus isoniazid combination therapy vs. isoniazid monotherapy

    University essay from Linnéuniversitetet/Institutionen för kemi och biomedicin (KOB)

    Author : Christinegie Khoury; [2021]
    Keywords : Latent tuberculosis infection; rifapentine; isoniazid;

    Abstract : Latent tuberculosis infection (LTBI) is a global health issue that affects approximately one quarter of the world’s population. It refers to a state of persistent immune response to Mycobacterium tuberculosis without clinical evidence of active tuberculosis (TB). READ MORE

  4. 4. Diagnos och behandling av Giardia duodenalis i en naturligt infekterad hundkoloni

    University essay from SLU/Dept. of Biomedical Sciences and Veterinary Public Health

    Author : Julia Svensson; [2021]
    Keywords : Giardia; hund; behandling; fenbendazol; metronidazol;

    Abstract : Giardia duodenalis är en flagellat som koloniserar främre tunntarmen och det är en vanlig parasit hos hundar över hela världen. Symptombilden vid giardiainfektion varierar då patogenesen för giardiasis är multifaktoriell och beror på faktorer hos både värddjuret och parasiten. G. READ MORE

  5. 5. Risk of neutropenia and healthcare resource utilization in patients with metastatic breast cancer treated with CDK4/6 inhibitors in real-world setting

    University essay from Örebro universitet/Institutionen för medicinska vetenskaper

    Author : Anna Bergkvist; [2021]
    Keywords : ;

    Abstract : Introduction: In patients with metastatic estrogen-receptor (ER) positive breast cancer, the current standard of care as first or second line treatment is a combination of endocrine therapy with a CDK 4/6-inhibitor. Neutropenia is a dose-limiting toxicity of CDK 4/6 inhibitors leading to dose adjustment and treatment discontinuation in a considerable number of patients. READ MORE