Essays about: "Clinical trials"

Showing result 1 - 5 of 86 essays containing the words Clinical trials.

  1. 1. An exploratory machine learning workflow for the analysis of adverse events from clinical trials

    University essay from Göteborgs universitet/Institutionen för matematiska vetenskaper

    Author : Margareta Carlerös; [2020-06-26]
    Keywords : Machine learning; Adverse events; Clinical trials; Data mining;

    Abstract : A new pharmaceutical drug needs to be shown to be safe and effective before it canbe used to treat patients. Adverse events (AEs) are potential side-effects that arerecorded during clinical trials, in which a new drug is tested in humans, and mayor may not be related to the drug under study. READ MORE

  2. 2. Censoring Bias in Oncology Clinical Trials

    University essay from Lunds universitet/Matematisk statistik

    Author : Andrea Mattsson; [2020]
    Keywords : survival analysis; censoring; progression-free survival; Cox proportional hazards model; oncology clinical trial; HER2CLIMB; Mathematics and Statistics;

    Abstract : Time to disease progression or death (PFS) is of main interest in oncology clinical trials. The data is commonly analyzed using a Cox model. Early discontinuation gives uncertainty in the estimated hazard ratio (HR). Censoring is generally used to handle discontinuations. READ MORE

  3. 3. Kontrollerad postanestetisk uppvakning med ett justerbart tak : fysiologiska effekter av stress hos shetlandsponnyer under uppvakningsperioden

    University essay from SLU/Dept. of Clinical Sciences

    Author : Lisa Nilson Hissa; Emelie Margareta Helena Törnqvist; [2020]
    Keywords : häst; anestesi; uppvakning; assisterad uppvakning; assisterad resning; stress;

    Abstract : Hästars uppvakning efter anestesi innebär många risker. Detta bidrar till att mortaliteten vid hästanestesi är mycket högre jämfört med mortaliteten vid anestesi av smådjur och människor. Hästars naturliga flyktbeteende gör ofta att de försöker resa sig innan narkosläkemedlen eliminerats. READ MORE

  4. 4. Ketamine for depression : The role of dissociative effects

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Jakob Broström; [2020]
    Keywords : antidepressant; depression; dissociation; ketamine; major depressive disorder; NMDA receptor antagonist; placebo; psychedelics;

    Abstract : Several trials have reported rapid antidepressant response from the anesthetic drug ketamine although the mechanism behind this effect is not fully understood. Research has focused mainly on ketamine’s action in the brain, including its effects on chemical balance, connections between brain cells and networks, and cognition. READ MORE

  5. 5. The Therapeutic Potential of Psilocybin and 3,4-Methylenedioxymethamphetamine in the Treatment of Depression and Post-Traumatic Stress Disorder

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Sofia Gyllvik; [2020]
    Keywords : 3; 4-methylenedioxymethamphetamine; MDMA; psilocybin; entactogen; psychedelic; psilocybin-assisted psychotherapy; MDMA-assisted psychotherapy;

    Abstract : The psychedelic psilocybin and the entactogen 3,4-methylenedioxymethamphetamine (MDMA) are being scientifically studied again after a long hiatus, and especially for their potential in the treatment of psychiatric disorders. Their profound effect on cognitive, perceptual, and affective processes have led to several clinical studies during the last decade that have forced the reconsideration of the utility of these substances. READ MORE