Essays about: "Combination therapy"

Showing result 1 - 5 of 76 essays containing the words Combination therapy.

  1. 1. Apoptosis induction in breast cancer cells after radiotherapy and potential radiosensitizers

    University essay from

    Author : Klara Simonsson; [2023-06-27]
    Keywords : Medical physics; Breast cancer cells; radiotherapy; systemic therapy; combination therapy; apoptosis; BH3 profiling; flow cytometry;

    Abstract : Background. Today breast cancer is the foremost cancer death type amongst women around the world. At present some of the toughest challenges in the clinic is recurrent, radioresistant breast cancer, and metastatic breast cancer where low cure rates are observed after surgery and radiotherapy. READ MORE

  3. 2. Combining doxorubicin and gemcitabine with targeted drugs as a treatment option for high-risk neuroblastoma

    University essay from KTH/Proteinvetenskap

    Author : Alexandra Johannesson; [2023]
    Keywords : neuroblastoma; doxorubicin; gemcitabine; targeted drugs; ATM; neuroblastom; doxorubicin; gemcitabin; målinriktade läkemedel; ATM;

    Abstract : Neuroblastom är en barncancer som uppstår ur det sympatiska nervsystemet och drabbar omkring 15 barn i Sverige varje år. Högriskvarianten är associerad med mycket hög dödlighet och risk för återfall, vilket tros ha att göra med att tumörernas ovanligt heterogena sammansättning tillåter resistenta subpopulationer att motstå konventionella behandlingsmetoder. READ MORE

  4. 3. Evaluating targeted combination therapies in EGFR wild-type non-small-cell lung cancer using mass spectrometry-based proteomics

    University essay from Lunds universitet/Institutionen för immunteknologi

    Author : Johan Thorsson; [2023]
    Keywords : Biology and Life Sciences;

    Abstract : Survival for non-small cell lung cancer (NSCLC) patients has been significantly improved by epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) in patients with EGFR mutations. However, certain subpopulations of NSCLC patients with EGFR wild-type (wt) status have been shown to also respond to EGFR-TKIs. READ MORE

  5. 4. Novel Therapy against Malaria Resistance using Meta-analysis

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Adesola Oguntuyi; [2022]
    Keywords : Malaria; Novel Drug; Resistance; ACT;

    Abstract : Malaria causes severe illness and death in some cases if not treated on time. The most vulnerable people are children and pregnant women in areas where it is rampant. The causative agent of the most severe malaria is Plasmodium falciparum this parasite is transmitted by the female anopheles mosquito when infected with Plasmodium parasites. READ MORE

  6. 5. Phenotypic profiling and drug screening in Rhabdomyosarcoma cell lines

    University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskap

    Author : Laura Martina Lang; [2022]
    Keywords : Rhabdomyosarcoma; Phenotypic profiling; Phenotypic drug screening;

    Abstract : Rhabdomyosarcoma (RMS) is a type of soft tissue sarcoma that mainly occurs in children. RMS can be divided into two subtypes embryonal (ERMS) and alveolar (ARMS). The ARMS subtype can be especially aggressive when a balanced chromosomal translocation is present. READ MORE