Essays about: "Cross- reactivity"

Showing result 1 - 5 of 22 essays containing the words Cross- reactivity.

1. 1. Immunological Cross-Reactivity : Construction of a Workflow That Enables Cross-Reactivity Predictions

   University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

   Author : Alexander Blomlöf; Alvin Unge; Petter Byström; Erika Lindberg; Torbjörn Fries; [2022]
   Keywords : Cross- reactivity; Immunology; Epitope; Paratope; Antibody; Prediction; Substitution analysis; Proximity Extension Assay; Bioinformatic tools;

   Abstract : Cross-reactivity occurs when an antibody binds to the epitope of a protein that is not the targeted antigen. This is problematic in the analysis of immunoassay diagnostics. Detecting a protein incorrectly might cause issues such as incorrect mapping of metabolic conditions for research or diagnosis. READ MORE

3. 2. Synthesis and Investigation of Nitrile-Containing Polymers Inspired by Lignin

   University essay from Lunds universitet/Centrum för analys och syntes

   Author : Tobias Lindborg; [2022]
   Keywords : Lignin; Polymer; Renewable; Bioresource; Glass transition temperature; Nitrile; Polymer technology; Chemistry; Technology and Engineering;

   Abstract : The lignin-inspired derivatives coniferyl aldehyde and sinapyl aldehyde were used to prepare nitrile-containing methacrylate monomers with the aim to synthesize bio-based polymers exhibiting high glass transition temperatures (Tgs). The aldehydes were initially transformed to the corresponding nitriles and then underwent methacrylation before being polymerised by free-radical polymerisation. READ MORE

4. 3. Photocatalytic activity of titanium dioxide thin films deposited with high power impulse magnetron sputtering

   University essay from Uppsala universitet/Fasta tillståndets elektronik

   Author : Victor Eriksson; [2021]
   Keywords : Photocatalysis; Titanium dioxide; Thin film; HiPIMS; Sputtering; Stearic acid;

   Abstract : High power impulse magnetron sputtering has shown a lot of promise as a way of depositing photocatalytic thin films of titanium dioxide at low temperatures, however, the films deposited are often amorphous and display uncertain photocatalytic abilities. This thesis explores the deposition and characterization of photocatalytic thin films deposited with high power impulse magnetron sputtering. READ MORE

5. 4. Validation of anti-cytokeratin antibodies used in rapid cancer diagnostics by isoelectric focusing and QCM technology

   University essay from Uppsala universitet/Biokemi

   Author : Reneh Kostines; [2021]
   Keywords : IEF; Isoelectric focusing; QCM; Attana; Cytokeratin; Keratin; Attana; Anti-cytokeratin; cancer; UBC; IDL; epithelial carcinomas; Antibody validation; Biosensor; Biosensors;

   Abstract : Antibodies are Y-shaped proteins. In the human body, antibodies areproduced by plasma cells, mainly T and B cells which are included inthe adaptive immune system. The production of antibodies is stimulatedby antigens. The binding between an antigen-specific antibody and itsantigen can be like the interconnect between a lock and a key. READ MORE

6. 5. Validation and optimization of multiplexInSitu PLA for signalling pathway analysis

   University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

   Author : Tanay Kumar Sinha; [2021]
   Keywords : Chronic myeloid leukemia Tyrosine kinase inhibitors Proximity ligation assay Cross-reactivity Padlock Template;

   Abstract : With the advent of Tyrosine kinase inhibitors (TKI) as a therapy for Chronic myeloid Leukemia (CML), the patients now enjoy a life expectancy close to that of the general population. But some patients do get unresponsive to the TKI treatment over time due to several mutations in the kinase domain of the BCR-ABL fusion protein, which further leads to activation of multiple signaling cascades within the leukemic cell, helping it survive and proliferate. READ MORE