Essays about: "Cytoscape"

Found 4 essays containing the word Cytoscape.

  1. 1. Gene Biomarker Identification by Distinguishing Between Small-Cell and Non-Small Cell Lung Cancer Through a Module-Based Approach

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Noor Haval Jamal; [2023]
    Keywords : ;

    Abstract : Lung cancer is the leading cause of cancer-related deaths worldwide and is divided into two broad histological types, small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). Network module-based approach is applied to lung cancer subtypes in order to analyze and compare the results with previous literature and thus discover new genetic biomarkers and/or confirm previously discovered ones. READ MORE

  2. 2. Explorative bioinformatic analysis of cardiomyocytes in 2D &3D in vitro culture system

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Sruthy Janardanan; [2021]
    Keywords : Cardiomyocytes; Pluripotent stem cells; 2D; 3D; differentially expressed genes; Hub nodes; Hub-Bottleneck nodes;

    Abstract : The in vitro cell culture models of human pluripotent stem cells (hPSC)-derived cardiomyocytes (CMs) have gained a predominant value in the field of drug discovery and is considered an attractive tool for cardiovascular disease modellings. However, despite several reports of different protocols for the hPSC-differentiation into CMs, the development of an efficient, controlled and reproducible 3D differentiation remains challenging. READ MORE

  3. 3. Bridging inflammatory bowel diseases and hepatobiliary disorders through pathway enrichment and module-based approach

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Alaa Saloum; [2020]
    Keywords : ;

    Abstract : Inflammatory bowel diseases (IBD) including Crohn’s disease (CD) and ulcerative colitis (UC) are associated with various hepatobiliary disorders. Two of the chronic hepatobiliary disorders that may coexist with inflammatory bowel diseases are: primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC). READ MORE

  4. 4. Quantifying metabolic fluxes using mathematical modeling

    University essay from Linköpings universitet/Institutionen för medicinsk teknik

    Author : Victor Viberg; [2018]
    Keywords : Metabolic Flux Analysis; OpenFlux; carbon thirteen; Uncertainty Analysis; Cytoscape; Cancer; TCA-cycle; flux rate; metabolic reactions; systems biology; mathematical modeling; krebs cycle; model validation;

    Abstract : Background Cancer is one of the leading causes of death in Sweden. In order to develop better treatments against cancer we need to better understand it. One area of special interest is cancer metabolism and the metabolic fluxes. As these fluxes cannot be directly measured, modeling is required to determine them. READ MORE