Essays about: "Cytotoxic effect"

Showing result 1 - 5 of 20 essays containing the words Cytotoxic effect.

  1. 1. A Single-Nucleus RNA Sequencing Analysis of HERVs and LINE1s in Alzheimer's and Parkinson's Disease

    University essay from Lunds universitet/Examensarbeten i bioinformatik

    Author : Stein Acker; [2022]
    Keywords : Biology and Life Sciences;

    Abstract : Transposable elements (TEs) are mobile genetic elements that make up roughly 50% of the human genome, with retrotransposons (or transposons which retrotranspose via an RNA intermediate) making up the vast majority of these elements. Recent studies have suggested that TEs could play a role in many neurological conditions, including ALS and dementia. READ MORE

  3. 2. Functionalization of nanofibrillated cellulose with the host defense peptide KR-12

    University essay from Uppsala universitet/Nanoteknologi och funktionella material

    Author : Alina Pavelescu; [2021]
    Keywords : KR-12; cellulose;

    Abstract : When the process of wound healing is disturbed, chronic wounds may develop. Chronic wounds heal very slowly over long periods of time, and require specialised care in order to prevent further infection. This causes considerable suffering to the patient and increased healthcare costs. READ MORE

  4. 3. Utilizing cytotoxic lymphocytes for indirect shock-and-kill strategy in HIV-1 treatment

    University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Author : Joana FIlipa Furtado Milão; [2021]
    Keywords : HIV-1; Shock-and-kill strategy; NK cells; latency reservoir; HIV-1 treatment;

    Abstract : Despite the existence of a treatment, there is still not a cure for HIV-1 infection and there arearound 700 000 deaths per year from AIDS-related diseases. A major barrier for a cure is theestablishment of latent reservoirs that are impossible to distinguish from healthy cells and thuscan escape the immune system. READ MORE

  5. 4. Ouabain Toxicity -Selectivity Towards Renal Cancer Cells

    University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Author : Emma Magnusson; [2020]
    Keywords : Cardiotonic steroids; ouabain; Na K -ATPase; cytotoxicity; renal cancer; apoptosis; Kardiotoniska steroider; ouabain; Na K -ATPase; cytotoxicitet; njurcancer; apoptos;

    Abstract : Ouabain and other cardiotonic steroids are known to inhibit Na + ,K + -ATPase (NKA), theion pump responsible for the ionic gradient across the plasma membrane. These steroidsdisplay a selective toxicity towards several tumour cells in comparison to primary humancells, however, the mechanism behind this is not yet understood. READ MORE

  6. 5. Exploring amino acid metabolism in Saccharomyces cerevisiae for improved eco-efficient production of chiral amine

    University essay from Malmö universitet/Fakulteten för hälsa och samhälle (HS)

    Author : Anna Karlsson; [2019]
    Keywords : 1-methyl-3-phenylpropylamine; amino acid; aminotransaminase; biotransformation; chiral amine; metabolically engineered; saccharomyces cerevisiae;

    Abstract : Kirala aminer används idag både som aktiva substanser och som bindningsmedel i flertalet läkemedel, dock är dagens produktion med kinetic resolution ineffektiv vilket gör att mer effektiva och miljövänliga produktionssätt eftersträvas. Biotransformation har visat sig både vara miljövänligt och en effektiv metod för att producera kirala aminer. READ MORE