Essays about: "DNA sequence analysis"

Showing result 21 - 25 of 66 essays containing the words DNA sequence analysis.

  1. 21. Supervised Learning for Prediction of Tumour Mutational Burden

    University essay from KTH/Matematisk statistik

    Author : Joanna Hargell; [2021]
    Keywords : Supervised Learning; Tumour Mutational Burden; Generalized Linear Models; Decision trees; Support Vector Machines; statistik; tillämpad matematik; statistisk inlärning; mutationsbörda;

    Abstract : Tumour Mutational Burden is a promising biomarker to predict response to immunotherapy. In this thesis, statistical methods of supervised learning were used to predict TMB: GLM, Decision Trees and SVM. READ MORE

  3. 22. Exploring DeepSEA CNN and DNABERT for Regulatory Feature Prediction of Non-coding DNA

    University essay from KTH/Skolan för elektroteknik och datavetenskap (EECS)

    Author : Jacob Stachowicz; [2021]
    Keywords : Machine Learning; Computer Science; Bioinformatics; Genomics; Transformer; Natural Language Processing; Whole Genome Sequencing; Non-codingDNA; DeepSEA; CNN; DNABert; BERT; DanQ; Biomedical Science; Computational Biology; AuROC; AUPRC; Maskininlärning; Datavetenskap; Bioinformatik; Genomik; Transformer; Språkteknologi; Helgenomsekvensering; icke-kod DNA; DeepSEA; CNN; DNABert; BERT; DanQ; Biomedicinsk vetenskap; Beräkningsbiologi; AuROC; AUPRC;

    Abstract : Prediction and understanding of the regulatory effects of non-coding DNA is an extensive research area in genomics. Convolutional neural networks have been used with success in the past to predict regulatory features, making chromatin feature predictions based solely on non-coding DNA sequences. READ MORE

  4. 23. The circadian rhythm of the cells is dependent of the pH of the cell

    University essay from Högskolan i Skövde/Institutionen för hälsovetenskaper

    Author : Maria Ines Berrojo Romeyro Mascarenhas; [2020]
    Keywords : ;

    Abstract : Circadian rhythms are endogenic autonomous oscillators of physiological activities resulting from 24-hour day/night cycles. Circadian rhythms regulate a wide variety of metabolic and physiological functions. This allows the organism to control its molecular, biochemical, physiological, and behavioural processes. READ MORE

  5. 24. Characterization of MITF gene in crayfish and their possible role in innate immunity

    University essay from SLU/Dept. of Animal Breeding and Genetics

    Author : Yaru Wen; [2020]
    Keywords : Microphthalmia-associated transcription factor; basic Helix-Loop-Helix Leucine Zipper; crayfish; Aphanomyces astaci; immunity;

    Abstract : Microphthalmia-associated transcription factor (MITF) is a tissue-specific transcription factor (TF), with a basic helix-loop-helix leucine zipper (bHLH-LZ) domain, which binds to the canonical E-box sequence (5’-CANNTG-3’) in the promoter region of target genes. In this study, the MITF-like protein was identified in the marbled crayfish (Procambarus virginalis). READ MORE

  6. 25. Development and validation of a novel quantitative PCR analysis method for HIV-1

    University essay from Lunds universitet/Tillämpad biokemi; Lunds universitet/Beräkningskemi

    Author : Josefine Sundgren; [2020]
    Keywords : HIV-1; qPCR; Octapharma; Taqman; applied biochemistry; tillämpad biokemi; Technology and Engineering;

    Abstract : The major problem when developing primers and probe sets for detection of HIV-1 is its high genetic variability and strong ability to mutate. HIV-1 is divided into four groups, M, N, O, P based on genetic similarities, and there are more than 70 different circulating recombinant forms. READ MORE