Essays about: "DNA-damage"

Showing result 1 - 5 of 24 essays containing the word DNA-damage.

1. 1. Combining doxorubicin and gemcitabine with targeted drugs as a treatment option for high-risk neuroblastoma

   University essay from KTH/Proteinvetenskap

   Author : Alexandra Johannesson; [2023]
   Keywords : neuroblastoma; doxorubicin; gemcitabine; targeted drugs; ATM; neuroblastom; doxorubicin; gemcitabin; målinriktade läkemedel; ATM;

   Abstract : Neuroblastom är en barncancer som uppstår ur det sympatiska nervsystemet och drabbar omkring 15 barn i Sverige varje år. Högriskvarianten är associerad med mycket hög dödlighet och risk för återfall, vilket tros ha att göra med att tumörernas ovanligt heterogena sammansättning tillåter resistenta subpopulationer att motstå konventionella behandlingsmetoder. READ MORE

3. 2. Toxicological analysis of Pyraclostrobin and Cyprodinilon Zebrafish larvae

   University essay from Örebro universitet/Institutionen för naturvetenskap och teknik

   Author : Kim Yeju; [2022]
   Keywords : gene expression; mixture effect; toxicity; pesticides; stress response;

   Abstract : Cyprodinil and pyraclostrobin are widely used pesticides to protect many plants from attack of microorganisms and fungal diseases. Although cyprodinil and pyraclostrobin exist in the aquatic environment at low concentration, their leftovers in the ecosystems lead to oxidative damage and interfere development in aquatic animals at environmental-relevant concentration. READ MORE

4. 3. The circadian rhythm of the cells is dependent of the pH of the cell

   University essay from Högskolan i Skövde/Institutionen för hälsovetenskaper

   Author : Maria Ines Berrojo Romeyro Mascarenhas; [2020]
   Keywords : ;

   Abstract : Circadian rhythms are endogenic autonomous oscillators of physiological activities resulting from 24-hour day/night cycles. Circadian rhythms regulate a wide variety of metabolic and physiological functions. This allows the organism to control its molecular, biochemical, physiological, and behavioural processes. READ MORE

5. 4. Comet assay: Monitoring time-dependent DNA-fragmentation in two different types of cells, optimizing Flash-comet method for pig sperm analysis

   University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskap

   Author : Ewelina Rozwadowska; [2020]
   Keywords : Comet assay; Flash-comet; cell survival curves; TK6-cells; pig sperm;

   Abstract : DNA-damage, caused by different factors such as oxidative stress in cells, is common in living organisms. The damage includes DNA-fragmentation, such as single- and double strands breaks. READ MORE

6. 5. Deciphering regulatory mechanism influencing qepA efflux pump expression in Escherichia coli

   University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

   Author : Jonas Gockel; [2020]
   Keywords : qepA; gene regulation; quinolone resistance; class 1 integron; lexA;

   Abstract : QepA is a plasmid-mediated efflux pump found in some strains of Escherichia coli, in which it significantly elevates the resistance against quinolones. The protein has similarities with 14-TMS major facilitator superfamily transporters and is situated in the inner membrane of the bacteria. READ MORE